Table 2 Baseline demographics, biomarkers and echocardiographic parameters of patients with and without diastolic dysfunction^a

Age (years)

50.82 ± 9.34

54.83 ± 9.8

11.85

0.001

Male

60 (60 %)

141 (64.7 %)

-

0.453

PCF (ml)

67.32 ± 31.95

86.79 ± 31.77

25.68

<0.001

TPAF (ml)

6.32 ± 3.73

8.63 ± 4.61

19.24

<0.001

BMI (kg/m²)

25.05 ± 3.78

25.36 ± 4.14

0.415

0.52

HbA1c (%)

4.84 ± 2.44

4.84 ± 2.48

<0.001

0.992

Cholesterol (mg/dL)

195.77 ± 45.85

203.94 ± 42.61

2.399

0.122

LDL (mg/dL)

124.72 ± 42.02

124.98 ± 46.85

0.002

0.963

Hs-CRP (mg/dL)

0.116 ± 0.039

0.166 ± 0.034

1.323

0.251

BNP (pg/mL)

21.03 ± 4.91

35.16 ± 6.7

3.572

0.06

Hypertension

29 (29 %)

73 (33.5 %)

-

0.441

Diabetes

12 (12 %)

34 (15.6 %)

-

0.493

Hyperlipidemia

40 (40 %)

69 (31.7 %)

-

0.162

LAD (mm)

28.76 ± 6.59

31.22 ± 6.08

10.64

0.001

E (cm/s)

68.81 ± 15.22

62.24 ± 16.23

11.7

0.001

DT (ms)

199.95 ± 35.88

210.04 ± 45.27

3.85

0.045

IVRT (ms)

85.66 ± 13.66

92.41 ± 15.49

13.98

<0.001

E’ (cm/s)

10 ± 1.59

6.7 ± 1.42

344.91

<0.001

E/E’

7.04 ± 1.85

9.63 ± 3.09

60.51

<0.001

Dias-D (ms)

22.62 ± 18.2

30.42 ± 21.66

9.793

0.002