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Table 5 Multivariate analysis of variables associated with disagreement among REGICOR (Framingham adapted to the Spanish population), UKPDS, and ADVANCE functions

From: Comparison of different vascular risk engines in the identification of type 2 diabetes patients with high cardiovascular risk

  REGICOR vs.
  UKPDS (OR; CI 95 %) ADVANCE (OR; CI 95 %)
Age centred (for year) 1.11 (1.08–1.15)* 1.42 (1.32–1.53)*
Gender (women) 0.23 (0.15–0.37)* 0.02 (0.008–0.05)*
Years since diabetes diagnosis   
 6–10 2.4 (1.38–4.15)** 189.2 (47.8–748.8)*
 11–20 18.1 (10.2–32.1)* 10.7 × 103 (1.7 × 103–65.4 × 103)*
  > 20 81.3 (22.2–297.6)* 2.06 × 105 (8.49 × 103–5.0 × 106)*
Non-HDL cholesterol (mg/dL) 1.012 (1.006–1.017)* 1.02 (1.01–1.03)*
HbA1c (for each 1 %) 1.39 (1.20–1.61)* 2.68 (2.03–3.52)*
Tobacco (yes) 1.41 (0.8–2.51) 2.6 (1.04–6.53)**
UAER (mg/gr) 0.999 (0.991–1.001) 1.01 (1.00–1.02)*
Pulse pressure (mmHg) 1.01 (0.99–1.03) 1.06 (1.03–1.09)*
Hypertension treatment (yes) 1.20 (0.75–1.92) 2.98 (1.37–6.45)**
Retinopathy (yes) 1.58 (0.81–3.09) 5.42 (1.83–16.0)**
  1. 0 = no disagreement, 1 = disagreement
  2. Adjusted for ethnicity, body mass index, waist circumference, diabetes therapy and type, systolic blood pressure, diastolic blood pressure, dyslipidaemia therapy and years since diabetes diagnosis
  3. UAER: urinary albumin excretion rate
  4. *p < 0.001
  5. **p < 0.05