Skip to main content

Table 5 Multivariate analysis of variables associated with disagreement among REGICOR (Framingham adapted to the Spanish population), UKPDS, and ADVANCE functions

From: Comparison of different vascular risk engines in the identification of type 2 diabetes patients with high cardiovascular risk

 

REGICOR vs.

 

UKPDS (OR; CI 95 %)

ADVANCE (OR; CI 95 %)

Age centred (for year)

1.11 (1.08–1.15)*

1.42 (1.32–1.53)*

Gender (women)

0.23 (0.15–0.37)*

0.02 (0.008–0.05)*

Years since diabetes diagnosis

  

 6–10

2.4 (1.38–4.15)**

189.2 (47.8–748.8)*

 11–20

18.1 (10.2–32.1)*

10.7 × 103 (1.7 × 103–65.4 × 103)*

  > 20

81.3 (22.2–297.6)*

2.06 × 105 (8.49 × 103–5.0 × 106)*

Non-HDL cholesterol (mg/dL)

1.012 (1.006–1.017)*

1.02 (1.01–1.03)*

HbA1c (for each 1 %)

1.39 (1.20–1.61)*

2.68 (2.03–3.52)*

Tobacco (yes)

1.41 (0.8–2.51)

2.6 (1.04–6.53)**

UAER (mg/gr)

0.999 (0.991–1.001)

1.01 (1.00–1.02)*

Pulse pressure (mmHg)

1.01 (0.99–1.03)

1.06 (1.03–1.09)*

Hypertension treatment (yes)

1.20 (0.75–1.92)

2.98 (1.37–6.45)**

Retinopathy (yes)

1.58 (0.81–3.09)

5.42 (1.83–16.0)**

  1. 0 = no disagreement, 1 = disagreement
  2. Adjusted for ethnicity, body mass index, waist circumference, diabetes therapy and type, systolic blood pressure, diastolic blood pressure, dyslipidaemia therapy and years since diabetes diagnosis
  3. UAER: urinary albumin excretion rate
  4. *p < 0.001
  5. **p < 0.05