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Table 3 Characteristics of high-risk patients according to each risk equation

From: Comparison of different vascular risk engines in the identification of type 2 diabetes patients with high cardiovascular risk

  REGICOR UKPDS ADVANCE
n = 312 n = 691 n = 737
Age, years, mean (SD) 64.1 (7.0) 66 (6.6) 68.1 (5.9)
Gender, men, n (%) 221 (70.8) 469 (67.9) 451 (61.2)
Years since diabetes diagnosis, mean (SD) 7.07 (5.4) 12.9 (6.5) 11.8 (7.1)
Afroamericans/Afrocaribbeans, n (%) 11 (3.5) 9 (1.3) 21 (2.8)
Tobacco, n (%) 118 (37.8) 122 (17.7) 86 (11.7)
BMI, kg/m2, mean (SD) 30.2 (4.7) 29.9 (4.6) 30.1 (4.9)
Waist circumference, cm, mean (SD) 100.2 (19.4) 100.0 (16.7) 101.0 (15.8)
Pulse pressure, mmHg, mean (SD) 59.2 (13.0) 61.8 (13.7) 63.9 (12.8)
Glycated haemoglobin, %, mean (SD) 7.4 (1.6) 7.7 (1.6) 7.4 (1.5)
HDL, mg/dL, mean (SD) 36.5 (8.1) 45.3 (12.0) 48.6 (12.8)
Non-HDL cholesterol 171.0 (42.5) 149.7 (38.4) 140.0 (37.4)
UAER, mg/gr, mean (SD) 37.3 (94.6) 43.5 (161.7) 55.1 (150.5)
GFR, mil/min/1.73 m2, mean (SD) 44 (96) 43 (94) 50 (101)
Diabetic retinopathy, n (%) 22 (7.1) 98 (14.2) 140 (19.0)
Diabetes therapy, n (%)    
 Diet 57 (18.3) 61 (8.8) 73 (10.0)
 OA 99 (31.7) 185 (26.8) 232 (31.7)
 OA + Insulin 66 (21.2) 152 (22.0) 143 (19.5)
 Insulin 18 (5.8) 66 (9.6) 78 (10.7)
 OA combined 70 (22.4) 221 (32.0) 206 (28.1)
Antihypertensive treatment, n (%) 226 (72.4) 491 (71.1) 589 (79.9)
Dyslipidaemia therapy, n (%) 168 (53.8) 375 (54.3) 421 (57.1)
  1. High risk is defined as follows: REGICOR ≥ 10 % at 10 years; UKPDS ≥ 15 % at 10 years
  2. ADVANCE ≥ 8 % at 4 years
  3. BMI body mass index, CBP clinic blood pressure, UAER urinary albumin excretion rate, GFR glomerular filtration rate according to MDRD equation, OA oral antidiabetic drug