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Table 3 Characteristics of high-risk patients according to each risk equation

From: Comparison of different vascular risk engines in the identification of type 2 diabetes patients with high cardiovascular risk

 

REGICOR

UKPDS

ADVANCE

n = 312

n = 691

n = 737

Age, years, mean (SD)

64.1 (7.0)

66 (6.6)

68.1 (5.9)

Gender, men, n (%)

221 (70.8)

469 (67.9)

451 (61.2)

Years since diabetes diagnosis, mean (SD)

7.07 (5.4)

12.9 (6.5)

11.8 (7.1)

Afroamericans/Afrocaribbeans, n (%)

11 (3.5)

9 (1.3)

21 (2.8)

Tobacco, n (%)

118 (37.8)

122 (17.7)

86 (11.7)

BMI, kg/m2, mean (SD)

30.2 (4.7)

29.9 (4.6)

30.1 (4.9)

Waist circumference, cm, mean (SD)

100.2 (19.4)

100.0 (16.7)

101.0 (15.8)

Pulse pressure, mmHg, mean (SD)

59.2 (13.0)

61.8 (13.7)

63.9 (12.8)

Glycated haemoglobin, %, mean (SD)

7.4 (1.6)

7.7 (1.6)

7.4 (1.5)

HDL, mg/dL, mean (SD)

36.5 (8.1)

45.3 (12.0)

48.6 (12.8)

Non-HDL cholesterol

171.0 (42.5)

149.7 (38.4)

140.0 (37.4)

UAER, mg/gr, mean (SD)

37.3 (94.6)

43.5 (161.7)

55.1 (150.5)

GFR, mil/min/1.73 m2, mean (SD)

44 (96)

43 (94)

50 (101)

Diabetic retinopathy, n (%)

22 (7.1)

98 (14.2)

140 (19.0)

Diabetes therapy, n (%)

   

 Diet

57 (18.3)

61 (8.8)

73 (10.0)

 OA

99 (31.7)

185 (26.8)

232 (31.7)

 OA + Insulin

66 (21.2)

152 (22.0)

143 (19.5)

 Insulin

18 (5.8)

66 (9.6)

78 (10.7)

 OA combined

70 (22.4)

221 (32.0)

206 (28.1)

Antihypertensive treatment, n (%)

226 (72.4)

491 (71.1)

589 (79.9)

Dyslipidaemia therapy, n (%)

168 (53.8)

375 (54.3)

421 (57.1)

  1. High risk is defined as follows: REGICOR ≥ 10 % at 10 years; UKPDS ≥ 15 % at 10 years
  2. ADVANCE ≥ 8 % at 4 years
  3. BMI body mass index, CBP clinic blood pressure, UAER urinary albumin excretion rate, GFR glomerular filtration rate according to MDRD equation, OA oral antidiabetic drug