Table 5 Factors independently associated with long term mortality following valve surgery in Cox proportional hazard modelling and the significance of the relationship of the model
From: A review of outcome following valve surgery for rheumatic heart disease in Australia
Hazard Ratio (95Â % CI) | All | RHD-related | Non-RHD |
|---|---|---|---|
 Age (/additional year) | 1.03 (1.02 – 1.04) | 1.03 (1.01 – 1.05) | 1.03 (1.02 – 1.04) |
Pre-operative comorbidities | |||
 Diabetes | 1.4 (1.2 – 1.6) | 1.7 (1.1 – 2.5) | 1.4 (1.2 – 1.6) |
 Chronic kidney disease | 1.5 (1.3 – 1.7) | 1.9 (1.2 – 2.9) | 1.4 (1.3 – 1.6) |
Pre-operative status | |||
 NYHA III & IV | 1.3 (1.1 – 1.4) | - | 1.3 (1.1 – 1.4) |
 Atrial fibrillation | 1.4 (1.2 – 1.6) | - | 1.5 (1.3 – 1.7) |
 LVEF >45 % | 0.7 (0.6 – 0.8) | - | 0.7 (0.6 – 0.8) |
Operative procedure | |||
 Mechanical valve | 0.8 (0.7 – 0.9) | - | 0.8 (0.7 – 0.9) |
 Valve repair only | 0.8 (0.6 – 0.9) | - | 0.8 (0.6 – 0.9) |
 Multiple valve surgery | - | - | 1.4 (1.1 – 1.7) |
Initial admission | |||
 ICU stay (>43 h) | 1.2 (1.1 – 1.4) | - | 1.3 (1.1 – 1.4) |
 Ventilation time (>11 h) | - | 1.7 (1.1 – 2.9) | - |
 Post procedure LOS (/additional day) | 1.01 (1.00 – 1.01) | 1.02 (1.01 – 1.03) | 1.00 (1.00 – 1.01) |
Complications within 30Â days | |||
 Readmission | 1.4 (1.2 – 1.6) | - | 1.4 (1.2 – 1.7) |
 Acute kidney injury | 1.9 (1.6 – 2.3) | - | 1.9 (1.6 – 2.3) |
 Stroke/ TIA | 1.6 (1.2 – 2.1) | - | 1.7 (1.3 – 2.2) |
 Septicaemia | 2.1 (1.6 – 2.8) | - | 2.2 (1.6 – 2.9) |
Significance of model (based on −2 Log Likelihood) | <0.001 | <0.001 | <0.001 |