Highly active antiretroviral therapy and dyslipidemia in people living with HIV/AIDS in Fako Division, South West Region of Cameroon

Table 4 Association of variables with abnormal lipid profile levels among HAART treated participants

Explanatory variables	TC ≥ 200 mg/dL UOR (95 % CI)	LDL-c ≥ 130 mg/dL UOR (95 % CI)	HDL-c < 40 mg/dL UOR (95 % CI)	TG ≥ 150 mg/dL UOR (95 % CI)
Gender (Female)	2.3 (1.03-4.98)	1.29 (0.58-2.89)	0.54 (0.20-1.44)	0.52 (0.22-1.25)
p-value	0.042	0.532	0.217	0.144
Age > 40 years	0.81 (0.43-1.56)	1.18 (0.61-2.31)	0.93 (0.36-2.37)	0.70 (0.30-1.60)
p-value	0.535	0.621	0.879	0.391
BMI ≥ 25 kg/m2	0.80 (0.42-1.51)	0.82 (0.43-1.59)	0.92 (0.37-2.30)	0.30 (0.12-0.75)
p-value	0.490	0.558	0.857	0.010
CD4⁺ T cell count < 200 cells/μl	0.80 (0.29-2.17)	0.72 (0.26-1.97)	0.58 (0.13-2.55)	0.64 (0.17-2.36)
p-value	0.652	0.518	0.468	0.506
HIV duration ≥ 42 months	0.51 (0.26-0.99)	0.59 (0.29-1.18)	0.66 (0.24-1.79)	0.36 (0.14-0.93)
p-value	0.045	0.136	0.413	0.035
HAART duration > 55 months	0.47 (0.25-0.90)	0.58 (0.30-1.11)	0.77 (0.31-1.92)	0.31 (0.13-0.74)
p-value	0.022	0.101	0.572	0.008
Hypertension	1.02 (0.49-2.10)	0.94 (0.44-2.00)	0.87 (0.30-2.54)	0.81 (0.32-2.06)
p-value	0.962	0.876	0.805	0.664
Diabetes Mellitus	0.47 (0.04-5.34)	0.85 (0.08-9.59)	NA	8.27 (0.73-94.2)
p-value	0.546	0.896	NA	0.089
Obesity	1.88 (0.90-3.92)	2.08 (1.00-4.32)	1.11 (0.40-3.08)	1.44 (0.61-3.38)
p-value	0.093	0.050	0.835	0.403
Alcohol intake	1.38 (0.59-3.24)	0.72 (0.29-1.78)	1.14 (0.35-3.70)	2.49 (0.99-6.27)
p-value	0.453	0.476	0.825	0.054

TC-Total Cholesterol, LDL-c-Low-Density Lipoprotein Cholesterol, HDL-c-High-Density Lipoprotein Cholesterol, TG-Triglyceride, HAART-Highly Active Antiretroviral Therapy, UOR-Unadjusted Odds Ratio, BMI-Body Mass Index, CD-Cluster of differentiation, NA- not applicable; Reference category: Male, Age ≤ 40 years, BMI < 25 kg/m², CD4⁺ T cell count ≥ 200 cells/μl, HIV duration < 42 months, HAART duration ≤ 55 months, non-hypertensive, non-diabetic, non-obese, no alcohol intake

ISSN: 1471-2261