Associations between risk factors in childhood (12–13 years) and adulthood (48–49 years) and subclinical atherosclerosis: the Kaunas Cardiovascular Risk Cohort Study

Table 2 Associations between intima-media thickness and variables measured in childhood and adulthood

Variable	Men			Women
Variable	β	95 % CI	P value	β	95 % CI	P value
Model 1
Childhood systolic BP, mm Hg (for a 1-SD change)	0.001	−0.001;0.003	0.357	0.014	0.003;0.025	0.016
Childhood BMI kg/m²	−0.002	−0.008;0.004	0.514	0.006	0.002;0.010	0.003
Sexual maturity score	−0.004	−0.016;0.009	0.570	−0.003	−0.006;0.001	0.183
R²	0.008			0.082
Model 2
Childhood systolic BP, mm Hg (for a 1-SD change)	0.002	−0.020;0.023	0.867	0.013	0.002;0.025	0.021
Childhood BMI kg/m²	−0.003	−0.10;0.004	0.380	0.003	−0.001;0.008	0.143
Sexual maturity score	−0.001	−0.014;0.011	0.853	−0.003	−0.007;0.001	0.147
Adult systolic BP, mm Hg (for a 1-SD change)	0.022	0.004;0.041	0.018	0.006	−0.006;0.018	0.320
HDL cholesterol mmol/l	−0.044	−0.082;-0.007	0.021	0.011	−0.017;0.040	0.431
LDL cholesterol mmol/l	0.002	−0.014;0.017	0.844	0.004	−0.006;0.014	0.390
Adult BMI, kg/m²	0.002	−0.002;0.006	0.363	0.002	−0.001;0.005	0.114
Daily smoking	0.006	−0.003;0.041	0.755	0.033	0.006;0.06	0.018
Education	0.001	−0.022;0.021	0.991	0.007	−0.006;0.021	0.292
R²	0.104			0.133

Reference group for daily smokers was nonsmokers and occasional smokers.
Abbreviations: BMI body mass index; BP blood pressure, CI confidence interval; HDL high-density lipoprotein; LDL low-density lipoprotein

ISSN: 1471-2261