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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: Elevated expression of periostin in diabetic cardiomyopathy and the effect of valsartan

Fig. 4

Immunohistochemical staining of periostin, TGF-β1, TGF-β1 R II, and Type I and III collagens in the control, DCM, and valsartan-treated group. The representative images of brown grain deposition showed the localization of the proteins. In contrast to the little or no protein staining in the control rat’s myocardium, the DCM rats displayed increased expression of above mentioned proteins in the heart, while the protein expressions were decreased in the valsartan-treated diabetic rats comparted to DCM group (×200)

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