Medication | Non-hyponatremia during hospitalization (n = 362) | Hyponatremia during hospitalization (n = 102) | P value |
---|---|---|---|
Furosemide | 95.3Â % | 95.1Â % | 0.931 |
ACEIs or ARBs | 77.3Â % | 64.7Â % | 0.01 |
Sparing diuretics | 24.3Â % | 29.4Â % | 0.296 |
Amiodarone | 15.5Â % | 22.5Â % | 0.093 |
Potassium supplement | 55.5Â % | 53.9Â % | 0.774 |
Positive inotropes | 9.1Â % | 31.4Â % | <0.001 |
Organic nitrates | 62.2Â % | 54.9Â % | 0.186 |
Digoxin | 25.1Â % | 26.5Â % | 0.785 |
Aspirin | 48.1Â % | 43.1Â % | 0.378 |
Clopidogrel | 28.7Â % | 33.3Â % | 0.369 |
Simvastatin | 46.4Â % | 41.2Â % | 0.348 |
Heparin | 9.1Â % | 18.6Â % | 0.007 |
Warfarin | 26.5Â % | 21.6Â % | 0.311 |
CCBs | 14.4Â % | 8.8Â % | 0.144 |
Ubiquinone | 14.7Â % | 10.8Â % | 0.314 |
Beta blockers | 13.5Â % | 9.8Â % | 0.318 |
Laxative agents | 40.9Â % | 38.2Â % | 0.630 |
PPIs | 14.9Â % | 22.5Â % | 0.069 |
H2RAs | 22.1Â % | 30.4Â % | 0.083 |
Allopurinol | 18.8Â % | 20.6Â % | 0.683 |
Benzodiazepine | 21.8Â % | 22.5Â % | 0.876 |
Insulin | 7.5Â % | 13.7Â % | 0.049 |
Oral anti-diabetics | 6.6Â % | 5.9Â % | 0.786 |
Antibiotics | 35.4Â % | 71.6Â % | <0.001 |
Beta blockers on discharge | 10.8Â % | 12.9Â % | 0.555 |
Length of hospital stay | 8 (5–12) | 11 (8–15) | <0.001 |
In-hospital death | 7.7Â % | 29.1Â % | <0.001 |