Table 1 VenUS IV participant characteristics at baseline

Male (n (%))

230 (50.7 %)

Age (years) (Mean (SD))

68.6 (14.5)

Body mass index (kg/m²) (Mean (SD))

31.0 (8.0)

Mobility

 Participant walks freely (n (%))

289 (63.8 %)

 Participant walks with difficulty (n (%))

160 (35.3 %)

 Participant is immobile (n (%))

4 (0.9 %)

SF-12 quality of life score (Mean (SD))^b

 Physical component

38.4 (11.2)

 Mental component

49.6 (11.3)

Diabetes

78 (17.2 %)

Ulcer area (cm²) (median (IQR))

3.9 (1.6, 8.7)

Ulcer duration (months)) (median (IQR))

4.0 (2.0, 11.0)

Time since first ulcer (months) (median (IQR))

36.0 (4.0, 120.0)

Total ulcers on reference leg (n) (median (IQR))

1.0 (1.0, 2.0)

Reference leg

 Left (n (%))

256 (56.4 %)

 Right (n (%))

198 (43.6 %)

Ankle mobility of reference leg (n (%))

 Participant has full range of motion

313 (68.9 %)

 Reduced range of ankle motion

132 (29.9 %)

 Participant’s ankle is fixed

9 (2.0 %)

Ankle brachial pressure index of reference leg (Mean (SD))

1.1 (0.1)