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Table 1 Characteristics of study population with or without lower extremity arterial stenosis

From: Association of plasma osteoprotegerin levels with the severity of lower extremity arterial disease in patients with type 2 diabetes

 

Without lower extremity arterial stenosis

Lower extremity arterial stenosis

p value

n

207

505

-

Age (years)

53.5 ± 12.1

65.3 ± 11.0

<0.001

Gender (male/female)

308/197

112/95

0.094

Duration of diabetes (years)

6.3 ± 5.9

10.6 ± 8.1

<0.001

smoking (%)

50 (24.3 %)

145 (28.7 %)

0.230

Hypertension (%)

86 (41.5 %)

326 (64.6 %)

<0.001

BMI (kg/m2)

25.1 ± 4.2

24.6 ± 3.4

0.184

WC (cm)

94.2 ± 13.1

91.9 ± 11.3

0.106

SBP (mmHg)

130.2 ± 15.1

132.4 ± 15.4

0.199

DBP (mmHg)

78.6 ± 11.5

76.2 ± 9.5

0.038

FPG (mmol/l)

8.5 ± 3.3

8.6 ± 3.2

0.719

HbA1c (%)

9.7 ± 2.5

9.5 ± 2.3

0.490

(mmol/mol)

83 ± 19.8

80 ± 18.2

0.490

Serum uric acid (mmol/l)

300.3 ± 90.7

303.9 ± 89.0

0.724

Total cholesterol (mmol/l)

4.5 ± 1.1

4.7 ± 1.1

0.091

triglycerides (mmol/l)

1.54 (1.04–2.23)

1.55 (1.03–2.25)

0.962

LDL-c (mmol/l)

2.7 ± 0.8

2.9 ± 0.7

0.122

HDL-c (mmol/l)

1.4 ± 0.3

1.3 ± 0.3

0.203

Adiponectin (mg/l)

9.2 ± 5.7

6.7 ± 4.4

<0.001

CRP (mg/l)

1.75 (0.77–5.38)

2.43 (0.81–5.47)

<0.001

Osteoprotegerin (ng/ml)

1.89 (1.48–2.41)

2.39 (1.82–3.33)

<0.001

Hypoglycemic treatments

  

0.001

Insulin (%)

78

188

 

OHA (%)

100

186

 

Insulin + OHA (%)

29

131

 
  1. Data are means ± SD, medians (interquartile range), or n (%). P values were obtained by an unpaired Student t test or χ2 analysis, as appropriate. BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol, OHA oral hypoglycemic agent