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Table 1 Characteristics of study population with or without lower extremity arterial stenosis

From: Association of plasma osteoprotegerin levels with the severity of lower extremity arterial disease in patients with type 2 diabetes

  Without lower extremity arterial stenosis Lower extremity arterial stenosis p value
n 207 505 -
Age (years) 53.5 ± 12.1 65.3 ± 11.0 <0.001
Gender (male/female) 308/197 112/95 0.094
Duration of diabetes (years) 6.3 ± 5.9 10.6 ± 8.1 <0.001
smoking (%) 50 (24.3 %) 145 (28.7 %) 0.230
Hypertension (%) 86 (41.5 %) 326 (64.6 %) <0.001
BMI (kg/m2) 25.1 ± 4.2 24.6 ± 3.4 0.184
WC (cm) 94.2 ± 13.1 91.9 ± 11.3 0.106
SBP (mmHg) 130.2 ± 15.1 132.4 ± 15.4 0.199
DBP (mmHg) 78.6 ± 11.5 76.2 ± 9.5 0.038
FPG (mmol/l) 8.5 ± 3.3 8.6 ± 3.2 0.719
HbA1c (%) 9.7 ± 2.5 9.5 ± 2.3 0.490
(mmol/mol) 83 ± 19.8 80 ± 18.2 0.490
Serum uric acid (mmol/l) 300.3 ± 90.7 303.9 ± 89.0 0.724
Total cholesterol (mmol/l) 4.5 ± 1.1 4.7 ± 1.1 0.091
triglycerides (mmol/l) 1.54 (1.04–2.23) 1.55 (1.03–2.25) 0.962
LDL-c (mmol/l) 2.7 ± 0.8 2.9 ± 0.7 0.122
HDL-c (mmol/l) 1.4 ± 0.3 1.3 ± 0.3 0.203
Adiponectin (mg/l) 9.2 ± 5.7 6.7 ± 4.4 <0.001
CRP (mg/l) 1.75 (0.77–5.38) 2.43 (0.81–5.47) <0.001
Osteoprotegerin (ng/ml) 1.89 (1.48–2.41) 2.39 (1.82–3.33) <0.001
Hypoglycemic treatments    0.001
Insulin (%) 78 188  
OHA (%) 100 186  
Insulin + OHA (%) 29 131  
  1. Data are means ± SD, medians (interquartile range), or n (%). P values were obtained by an unpaired Student t test or χ2 analysis, as appropriate. BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol, OHA oral hypoglycemic agent