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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Role of SIRT3 in Angiotensin II-induced human umbilical vein endothelial cells dysfunction

Fig. 3

Knockdown of SIRT3 worsen the AngII-induced effects on HUVECS. Cells transfected with negative control siRNA or SIRT3 siRNA were then treatment with AngII for 24 h. SIRT3 expression were determined by western blot in each group (a) and Quantification of SIRT3 in each group, β-actin as a reference (c). eNOS expression were determined by western blot in each group (b) and Quantification of eNOS in each group, β-actin as a reference (d). eNOS activity in each group (e), NO concentration in each group (f). Data are the mean ± SEM from three separate experiments. *P < 0.05 vs. Negative Control (NC), #P < 0.05 vs. AngII group

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