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Table 5 Description of Excluded RCTs

From: Colchicine in cardiac disease: a systematic review and meta-analysis of randomized controlled trials

Excluded Trial

Patient Inclusion

Number of Patients/Centres

Intervention

Control

Follow Up Duration

Outcomes

Reason for Exclusion

Prevention of Post-Op Afib

Saenen et al. Eur Heart J 2013 [Abstract] [38]

Post CABG

40/single

Peri-operative Colchicine

Placebo

1 hour post CABG

Right Atrial Appendage Biopsy Pathology

Only pathology data provided

Nidorf & Thompson Am J Card 2007 [39]

Stable CAD

64/single

Colchicine

Control

4 weeks

C-reactive protein

Not randomized

Freed et al. Am J Card 1995 [40]

Post PTCA

5/single

Cochicine + Enalapril + Lovastatin

n/a

5 months

Death, MI, revasc.

Not randomized

Rab et al. JACC 1991 [41]

Post BMS PTCA

29/single

Colchicine + gluco-corticoids

Gluco-corticoids

4 months

Coronary artery aneurysm

Not randomized

Judkins et al. Heart Lung Circ 2011 [Abstract] [42]

Stable CAD

50/single

Colchicine

Control

6 months

C-reactive protein; flow mediated dilation

Cross over RCT

Luo & Yang. Hong Kong Med J 2001 [Abstract] [43]

Acute stroke

n/a

Colchicine, Cyclo-phosphamide plus Magnesium

Control

n/a

n/a

Combined intervention

Xu et al. West China Med J 1999 [Chinese] [44]

Acute stroke

64/single

Colchicine and Cyclo-phosphamide

Control

3 months

Neurological outcomes

Combined intervention

Liu et al. Chin J Geriat Cardiovasc Cerebrovasc Dis 2002 [Chinese] [45]

Acute stroke

325/multi

Colchicine and Cyclo-phosphamide

Control

3 months

Neurological outcomes, serum enolase, adverse events

Combined intervention

  1. Abbreviations: BMS bare metal stent, CABG coronary artery bypass grafting, CAD coronary artery disease, MI myocardial infarction, n/a not available, PTCA percutaneous coronary angioplasty, RCT randomized controlled trial