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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: Colchicine in cardiac disease: a systematic review and meta-analysis of randomized controlled trials

Fig. 4

Forest Plot for Pericarditis and Post Cardiac Surgery Pericardiotomy. Individual and pooled risk ratios (RR) with 95 % confidence intervals (CI) for randomized controlled trials (RCTs) comparing colchicine to placebo or control in patients with pericarditis or post cardiac surgery pericardiotomy. The pooled RRs with 95 % CI were calculated using random-effects models. Weight refers to the contribution of each study to the overall pooled estimate of treatment effect. Each square and horizontal line denotes the point estimate and 95 % CI for each trial’s RR. The diamonds signify the pooled RR; the diamond’s centre denotes the point estimate and width denotes the 95 % CI. The decreases in risks were similar for pericarditis vs. pericardiotomy RCTs (interaction p = 0.28), and, as described in the manuscript text, also for acute vs. recurrent vs. multiple recurrent pericarditis RCTs with non-significant interaction p-values for all comparisons

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