Performance of Sokolow-Lyon index in detection of echocardiographically diagnosed left ventricular hypertrophy in a normal Eastern German population - results of the CARLA study

Table 3 Linear regression of echocardiographic parameters on the Sokolow-Lyon index within considered BMI categories, and respective interaction analyses

	BMI (kg/m²)	Crude beta^a (95 % CI)	p	p (interaction)*	Adjusted beta^a,b (95 % CI)	p	p (interaction)*
LVMI (g/m²)	<25	6.34 (1.58, 11.10)	0.0092		4.79 (0.47, 9.11)	0.0041
	25–29.9	6.09 (1.86, 10.33)	0.0049	0.0389	5.51 (1.75, 9.27)	0.001	0.0244
	≥30	9.55 (3.81, 15.30)	0.0012		9.24 (3.75, 14.73)	0.001
LVIDd (cm/m²)	<25	0.05 (0.00, 0.09)	0.0384		0.03 (−0.01, 0.07)	0.1306
	25–29.9	0.10 (0.06, 0.13)	<0.0001	0.3948	0.08 (0.05, 0.12)	<0.0001	0.1280
	≥30	0.08 (0.04, 0.12)	0.0002		0.07 (0.02, 0.11)	0.0031
PWTd (cm)	<25	0.02 (−0.01, 0.04)	0.2255		0.01 (−0.01, 0.03)	0.4774
	25–29.9	0.00 (−0.02, 0.02)	0.9225	0.3672	−0.01 (−0.03, 0.01)	0.5528	0.4426
	≥30	0.02 (−0.01, 0.04)	0.2604		0.02 (−0.01, 0.04)	0.2478
SWTd (cm)	<25	0.01 (−0.01, 0.04)	0.3217		0.01 (−0.01, 0.03)	0.4411
	25–29.9	0.01 (−0.02, 0.03)	0.624	0.6835	0.00 (−0.02, 0.02)	0.8048	0.9081
	≥30	0.01 (−0.02, 0.03)	0.4979		0.01 (−0.02, 0.03)	0.5193

SLI Sokolow-Lyon index, LVMI left-ventricular mass index, LVIDd left-ventricular internal diameter at end-diastole index, PWTd left-ventricular posterior wall thickness at end-diastole, SWTd septal wall thickness at end-diastole, 95 % CI 95 % confidence interval
*p-value of the multiplicative interaction of the SLI with considered BMI classes
^aadjusted for sex, sport index, smoking status, NT-pro BNP, low density lipoprotein, arterial hypertension, waist-to-hip ratio, diabetes mellitus, regular intake of antiarrhythmic medication, beta blockers and digitalis glycosides
^bBeta gives the increase of the respective echocardiographic parameter per mV increase of the SLI

ISSN: 1471-2261