Platelet volume indices are associated with systolic and diastolic cardiac dysfunction, and left ventricular hypertrophy

Table 3 Multivariate logistic regression analysis of factors associated with LVSD

Independent variables	Odds ratio (95 % CI)	P value	Odds ratio (95 % CI)	P value
	model 1		model 2
Sex (male = 1)	1.08 (0.74–1.58)	0.700	1.07 (0.73–1.56)	0.743
Age, per 1SD	0.83 (0.71–0.97)	0.018	0.83 (0.71–0.97)	0.017
Systolic blood pressure, per 1SD	0.87 (0.75–1.01)	0.059	0.87 (0.75–1.01)	0.062
Chronic kidney disease	1.56 (1.03–2.36)	0.036	1.60 (1.05–2.43)	0.027
Any antiplatelet drugs	1.00 (0.72–1.38)	0.997	0.98 (0.71–1.35)	0.888
Warfarin	2.18 (1.58–2.99)	<0.001	2.18 (1.58–2.99)	<0.001
White blood cell count, per 1SD	1.19 (1.03–1.37)	0.016	1.18 (1.03–1.36)	0.017
Hemoglobin, per 1SD	0.78 (0.67–0.90)	0.001	0.79 (0.68–0.91)	0.001
Platelet count, per 1SD	0.90 (0.76–1.06)	0.206
MPV, per 1SD	1.15 (0.98–1.35)	0.096
PDW, per 1SD	1.25 (1.06–1.46)	0.007
Middle platelet tertile			0.80 (0.56–1.14)	0.218
Highest platelet tertile			0.83 (0.56–1.23)	0.346
Middle MPV tertile			1.18 (0.80–1.73)	0.412
Highest MPV tertile			1.53 (1.04–2.27)	0.033
Middle PDW tertile			1.80 (1.22–2.64)	0.003
Highest PDW tertile			2.03 (1.37–3.02)	<0.001

In model 2, platelet indices used in model 1 were used replaced by tertile of these variables, and the odds ratio of the middle and the highest tertile was calculated using the corresponding lowest tertile

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