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Table 2 Association study of four SNPs in PAPP-A under different models in two groups

From: Correlation of single nucleotide polymorphisms in the pregnancy-associated plasma protein-A gene with carotid plaques

  Carotid plaque Controls  
Analyzing Model: SNPs n1 Frequency (%) n1 Frequency (%) P value §
rs3747823      
Additive: GG/AG/AA 263/126/18 64.6/31.0/4.4 298/155/27 62.1/32.3/5.6 NS
Dominant: (AA + AG)/GG 144/263 35.4/64.6 182/298 38.0/62.0 NS
Recessive: AA/(AG + GG) 18/389 4.4/95.6 27/453 5.6/94.4 NS
rs7020782      
Additive: AA/AC/CC 166/190/51 40.8/46.7/12.5 302/159/29 61.6/32.4/6.0 <0.001
Dominant: (AC + CC)/AA 241/166 59.2/40.8 188/302 38.4/61.6 <0.001
recessive: CC/(AC + AA) 51/356 12.5/87.5 29/461 5.9/94.1 0.001
rs13290387      
Additive: GG/CG/CC 207/163/31 51.6/40.6/7.7 269/179/35 55.7/37.1/7.2 NS
Dominant: (CG + CC)/GG 194/207 48.4/51.6 214/269 44.3/55.7 NS
Recessive: CC/(CG + GG) 31/370 7.7/92.3 35/448 7.2/92.8 NS
  1. §P-values were calculated by Pearson Chi-Squared test. NS, no significance
  2. 1The number did not add up to 408 or 493, because the SNPs genotyping with LDR method had the absent value inevitably