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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Enhanced expression of ROCK in left atrial myocytes of mitral regurgitation: a potential mechanism of myolysis

Fig. 2

Immunofluorescence images of the normal human adult left atrial tissue sample (left panel, A), left atrial tissue of mitral regurgitation patients with sinus rhythm (middle panel, B), and left atrial tissue of mitral regurgitation patients with atrial fibrillation (AF) (right panel, C). Numerous myocytes with perinuclear sarcomere depletion (myolysis) (arrows) were found in mitral regurgitation patients with sinus and mitral regurgitation patients with AF. Whereas in normal control atrial sample, myofibrils were organized in a well-aligned and striated network (no myolysis in the myocytes in panel A). Myocyte identification was performed with phalloidin-FITC F-actin (green color). Bar = 20 μm.

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