Skip to main content

Table 3 Coefficients, standard error of coefficients and p-values for the joint model predicting death and aortic valve intervention

From: Dynamic prediction of outcome for patients with severe aortic stenosis: application of joint models for longitudinal and time-to-event data

  Coef Exp(coef):HR Se(coef) p-value
Death     
BNP at specific time point (pg/ml) 0.5 1.65 0.3 0.0962
AVA (cm2) −2.61 0.07 1.5 0.0815
Age (years) 0.02 1.02 0.04 0.5674
Male gender 1.12 3.06 0.6 0.0623
Symptoms 1.87 6.49 1.05 0.0753
*LV ejection fraction (%) 0.01 1.01 0.25 0.9539
*Creatinine (micromol/L) 0.18 1.2 0.15 0.2162
Aortic valve intervention     
BNP at specific time point (pg/ml) 0.18 1.2 0.25 0.4787
AVA (cm2) −1.12 0.33 1.04 0.2804
Age (years) −0.04 0.96 0.02 0.0077
Male gender 0.39 1.48 0.49 0.4287
Symptoms 1.08 2.94 0.46 0.0183
*LV ejection fraction (%) 0.24 1.27 0.21 0.2388
*Creatinine (micromol/L) −1.43 0.24 1.31 0.2761
  1. BNP = brain natriuretic peptide; AVA = aortic valve area; LV = left ventricular; HR = hazard ratio. * Trasnformed LV ejection fraction and Creatinine in the models