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Table 2 Coefficients, standard error of coefficients and p-values for the mixed-effects model describing the evolution of BNP over time

From: Dynamic prediction of outcome for patients with severe aortic stenosis: application of joint models for longitudinal and time-to-event data

  Coef Se(coef) p-value
(Intercept) 2.92 0.95 0.0025
Time (years) 0.23 0.04 <0.0001
AVA (cm2) −1.48 0.3 <0.0001
Age (years) 0.05 0.007 <0.0001
Symptoms 0.43 0.18 0.0188
Male gender −0.34 0.18 0.0607
*LV ejection fraction (%) −0.16 0.08 0.0486
*Creatinine (micromol/L) 0.4 0.09 <0.0001
  1. AVA = aortic valve area; LV = left ventricular. * Trasnformed LV ejection fraction and Creatinine in the models