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Table 2 Coefficients, standard error of coefficients and p-values for the mixed-effects model describing the evolution of BNP over time

From: Dynamic prediction of outcome for patients with severe aortic stenosis: application of joint models for longitudinal and time-to-event data

 

Coef

Se(coef)

p-value

(Intercept)

2.92

0.95

0.0025

Time (years)

0.23

0.04

<0.0001

AVA (cm2)

−1.48

0.3

<0.0001

Age (years)

0.05

0.007

<0.0001

Symptoms

0.43

0.18

0.0188

Male gender

−0.34

0.18

0.0607

*LV ejection fraction (%)

−0.16

0.08

0.0486

*Creatinine (micromol/L)

0.4

0.09

<0.0001

  1. AVA = aortic valve area; LV = left ventricular. * Trasnformed LV ejection fraction and Creatinine in the models