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Table 3 pHi values and concentrations of ATP and pCr in whole heart preparations treated at varying doses of triptolide

From: Triptolide improves systolic function and myocardial energy metabolism of diabetic cardiomyopathy in streptozotocin-induced diabetic rats

  Control TP DM DM + TP, L DM + TP, M DM + TP, H
pHi 7.26 ± 0.12 7.24 ± 0.14 7.20 ± 0.12* 7.22 ± 0.12 7.24 ± 0.12# 7.23 ± 0.12
ATP (mmol/L) 0.17 ± 0.03 0.18 ± 0.01 0.07 ± 0.01* 0.10 ± 0.02*# 0.13 ± 0.02*# 0.14 ± 0.01*#
pCr (mmol/L) 21.3 ± 1.3 21.5 ± 2.8 13.7 ± 1.3* 16.6 ± 1.7*# 18.8 ± 2.3*# 18.9 ± 2.2*#
  1. TP,L low-dose triptolide (100 μg/kg/day), TP,M medium-dose triptolide (200 μg/kg/day), TP,H high-dose triptolide (400 μg/kg/day). *P < 0.05 versus Control; #P < 0.05 versus DM