Skip to main content

Table 3 pHi values and concentrations of ATP and pCr in whole heart preparations treated at varying doses of triptolide

From: Triptolide improves systolic function and myocardial energy metabolism of diabetic cardiomyopathy in streptozotocin-induced diabetic rats

 

Control

TP

DM

DM + TP, L

DM + TP, M

DM + TP, H

pHi

7.26 ± 0.12

7.24 ± 0.14

7.20 ± 0.12*

7.22 ± 0.12

7.24 ± 0.12#

7.23 ± 0.12

ATP (mmol/L)

0.17 ± 0.03

0.18 ± 0.01

0.07 ± 0.01*

0.10 ± 0.02*#

0.13 ± 0.02*#

0.14 ± 0.01*#

pCr (mmol/L)

21.3 ± 1.3

21.5 ± 2.8

13.7 ± 1.3*

16.6 ± 1.7*#

18.8 ± 2.3*#

18.9 ± 2.2*#

  1. TP,L low-dose triptolide (100 μg/kg/day), TP,M medium-dose triptolide (200 μg/kg/day), TP,H high-dose triptolide (400 μg/kg/day). *P < 0.05 versus Control; #P < 0.05 versus DM
Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us