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Table 1 Baseline characteristics of 401 patients initially presenting with acute dyspnea or peripheral edema

From: Ischemic biomarker heart-type fatty acid binding protein (hFABP) in acute heart failure - diagnostic and prognostic insights compared to NT-proBNP and troponin I

Variables All patients No AHF AHF p value*
(n = 401) (n = 279) (n = 122)
Demographics     
 Age, mean (range) 67 (18–96) 65 (18–96) 73 (36–96) 0.0001
 Male, n (%) 205 (51) 131 (47) 74 (61) 0.7
Cardiovascular risk factors, n (%)     
 Arterial hypertension 268 (67) 170 (61) 98 (80) 0.0001
 Hypercholesterinemia 122 (30) 207 (74) 72 (59) 0.003
 Cardiac family history 132 (33) 97 (35) 35 (27) 0.3
 Smoking 206 (51) 148 (53) 58 (48) 0.3
 Diabetes mellitus 120 (30) 67 (24) 53 (43) 0.0001
Main diagnoses, n (%)     
 Chronic CHF 143 (36) 63 (23) 80 (66) 0.0001
 Atrial fibrillation 90 (22) 40 (14) 50 (41) 0.0001
 Coronary artery disease 130 (32) 73 (26) 57 (47) 0.0001
 Prior myocardial Infarction 89 (22) 47 (17) 42 (34) 0.0002
 Valvular heart disease 118 (29) 48 (17) 70 (57) 0.0001
 Acute exacerbated COPD 31 (8) 27 (10) 4 (3) 0.03
 Acute exacerbated asthma 7 (2) 7 (3) 0 (0) 0.1
 Pneumonia 20 (5) 19 (7) 1 (1) 0.01
 Pulmonary embolism 12 (3) 12 (4) 0 (0) 0.02
 Chronic kidney disease 71 (17) 30 (11) 41 (34) 0.0001
 Cancer 19 (5) 19 (7) 0 (0) 0.001
 Stroke 10 (2) 8 (3) 2 (2) 0.7
 LV EF (%), median (interquartile range) 41 (30–52) 50 (40–58) 39 (27–50) 0.04
Symptoms and signs, n (%)     
 Peripheral edema 46 (11) 42 (15) 4 (3) 0.02
 Dyspnea 235 (59) 183 (66) 52 (42) 0.0001
 Both peripheral edema and dyspnea 120 (30) 54 (19) 66 (54) 0.0001
  1. *p values for the comparison between AHF and no AHF group