Molecular mechanisms behind progressing chronic inflammatory dilated cardiomyopathy

Table 3 Correlation of apoptotic, necrotic and inflammatory biomarkers in EMB

	Casp-9 in biopsy	Casp-8 in biopsy	Casp-3 in biopsy	Bcl2 in biopsy	FasR in biopsy	FasL in biopsy	MMP9 in biopsy	TIMP1 in biopsy	Bax in biopsy	IL-6 in serum
Casp-8 in biopsy	0.303
Casp-3 in biopsy	0.063	0.436*
Bcl2 in biopsy	−0.202	0.175	0.486*
FasR in biopsy	−0.097	−0.074	0.526*	0.739**
FasL in biopsy	−0.046	0.007	0.442*	0.835**	0.907**
MMP9 in biopsy	−0.229	0.024	0.419	0.764**	0.730**	0.824**
TIMP1 in biopsy	−0.012	−0.205	0.213	0.517*	0.795**	0.722**	0.401
Bax in biopsy	0.283	0.584**	0.678**	0.056	0.139	0.053	0.128	−0.127
IL-6 in serum	0.518*	−0.016	−0.011	−0.262	−0.202	−0.154	−0.041	−0.227	0.131
hs TNT in serum	0.434	0.598**	0.563*	−0.125	−0.067	−0.165	−0.120	−0.249	0.954**	0.231

Two tailed significance: *P < 0.05; **P < 0.01. Significant correlations are in bold type.
Abbreviations: Casp-3 – Caspase-3; Casp-8 – Caspase-8; Casp-9 – Caspase-9; IL-6 – Interleukin-6; Bcl-2 – B-cell lymphoma 2 protein; FasR—Fas receptor; FasL – Fas ligand; MMP9 – matrix metalloproteinase 9; TIMP1 – tissue inhibitor of matrix metalloproteinase 1; Bax – Bcl-2–associated X protein; Hsp60 – heat shock protein 60; hsTnT – high sensitivity Troponin T.

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