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Table 3 Correlation of apoptotic, necrotic and inflammatory biomarkers in EMB

From: Molecular mechanisms behind progressing chronic inflammatory dilated cardiomyopathy

  Casp-9 in biopsy Casp-8 in biopsy Casp-3 in biopsy Bcl2 in biopsy FasR in biopsy FasL in biopsy MMP9 in biopsy TIMP1 in biopsy Bax in biopsy IL-6 in serum
Casp-8 in biopsy 0.303          
Casp-3 in biopsy 0.063 0.436*         
Bcl2 in biopsy −0.202 0.175 0.486*        
FasR in biopsy −0.097 −0.074 0.526* 0.739**       
FasL in biopsy −0.046 0.007 0.442* 0.835** 0.907**      
MMP9 in biopsy −0.229 0.024 0.419 0.764** 0.730** 0.824**     
TIMP1 in biopsy −0.012 −0.205 0.213 0.517* 0.795** 0.722** 0.401    
Bax in biopsy 0.283 0.584** 0.678** 0.056 0.139 0.053 0.128 −0.127   
IL-6 in serum 0.518* −0.016 −0.011 −0.262 −0.202 −0.154 −0.041 −0.227 0.131  
hs TNT in serum 0.434 0.598** 0.563* −0.125 −0.067 −0.165 −0.120 −0.249 0.954** 0.231
  1. Two tailed significance: *P < 0.05; **P < 0.01. Significant correlations are in bold type.
  2. Abbreviations: Casp-3 – Caspase-3; Casp-8 – Caspase-8; Casp-9 – Caspase-9; IL-6 – Interleukin-6; Bcl-2 – B-cell lymphoma 2 protein; FasR—Fas receptor; FasL – Fas ligand; MMP9 – matrix metalloproteinase 9; TIMP1 – tissue inhibitor of matrix metalloproteinase 1; Bax – Bcl-2–associated X protein; Hsp60 – heat shock protein 60; hsTnT – high sensitivity Troponin T.