TY - JOUR AU - Goff, D. C. AU - Lloyd-Jones, D. M. AU - Bennett, G. AU - Coady, S. AU - D’Agostino, R. B. AU - Gibbons, R. PY - 2014 DA - 2014// TI - 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines JO - Circulation VL - 129 UR - https://doi.org/10.1161/01.cir.0000437741.48606.98 DO - 10.1161/01.cir.0000437741.48606.98 ID - Goff2014 ER - TY - JOUR AU - Ross, R. PY - 1999 DA - 1999// TI - Atherosclerosis–an inflammatory disease JO - N Engl J Med VL - 340 UR - https://doi.org/10.1056/NEJM199901143400207 DO - 10.1056/NEJM199901143400207 ID - Ross1999 ER - TY - JOUR AU - Libby, P. PY - 2005 DA - 2005// TI - Act local, act global: inflammation and the multiplicity of “vulnerable” coronary plaques JO - J Am Coll Cardiol VL - 45 UR - https://doi.org/10.1016/j.jacc.2005.02.058 DO - 10.1016/j.jacc.2005.02.058 ID - Libby2005 ER - TY - JOUR AU - Kiechl, S. AU - Willeit, J. AU - Mayr, M. AU - Viehweider, B. AU - Oberhollenzer, M. AU - Kronenberg, F. PY - 2007 DA - 2007// TI - Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study JO - Arterioscler Thromb Vasc Biol VL - 27 UR - https://doi.org/10.1161/ATVBAHA.107.145805 DO - 10.1161/ATVBAHA.107.145805 ID - Kiechl2007 ER - TY - JOUR AU - Ridker, P. M. AU - Hennekens, C. H. AU - Buring, J. E. AU - Rifai, N. PY - 2000 DA - 2000// TI - C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women JO - N Engl J Med VL - 342 UR - https://doi.org/10.1056/NEJM200003233421202 DO - 10.1056/NEJM200003233421202 ID - Ridker2000 ER - TY - JOUR AU - Macphee, C. H. AU - Nelson, J. AU - Zalewski, A. PY - 2006 DA - 2006// TI - Role of lipoprotein-associated phospholipase A2 in atherosclerosis and its potential as a therapeutic target JO - Curr Opin Pharmacol VL - 6 UR - https://doi.org/10.1016/j.coph.2005.11.008 DO - 10.1016/j.coph.2005.11.008 ID - Macphee2006 ER - TY - JOUR AU - Daniels, L. B. AU - Laughlin, G. A. AU - Sarno, M. J. AU - Bettencourt, R. AU - Wolfert, R. L. AU - Barrett-Connor, E. PY - 2008 DA - 2008// TI - Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo Study JO - J Am Coll Cardiol VL - 51 UR - https://doi.org/10.1016/j.jacc.2007.10.048 DO - 10.1016/j.jacc.2007.10.048 ID - Daniels2008 ER - TY - JOUR AU - Gerber, Y. AU - McConnell, J. P. AU - Jaffe, A. S. AU - Weston, S. A. AU - Killian, J. M. AU - Roger, V. L. PY - 2006 DA - 2006// TI - Lipoprotein-associated phospholipase A2 and prognosis after myocardial infarction in the community. downloaded JO - Arterioscler Thromb Vasc Biol VL - 26 UR - https://doi.org/10.1161/01.ATV.0000240406.89440.0c DO - 10.1161/01.ATV.0000240406.89440.0c ID - Gerber2006 ER - TY - JOUR AU - Ballantyne, C. M. AU - Hoogeveen, R. C. AU - Bang, H. AU - Coresh, J. AU - Folsom, A. R. AU - Heiss, G. PY - 2004 DA - 2004// TI - Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study JO - Circulation VL - 109 UR - https://doi.org/10.1161/01.CIR.0000116763.91992.F1 DO - 10.1161/01.CIR.0000116763.91992.F1 ID - Ballantyne2004 ER - TY - JOUR AU - Mohler, E. R. AU - Ballantyne, C. M. AU - Davidson, M. H. AU - Hanefeld, M. AU - Ruilope, L. M. AU - Johnson, J. L. PY - 2008 DA - 2008// TI - The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study JO - J Am Coll Cardiol VL - 51 UR - https://doi.org/10.1016/j.jacc.2007.11.079 DO - 10.1016/j.jacc.2007.11.079 ID - Mohler2008 ER - TY - JOUR AU - Berger, J. S. AU - Ballantyne, C. M. AU - Davidson, M. H. AU - Johnson, J. L. AU - Tarka, E. A. AU - Lawrence, D. PY - 2011 DA - 2011// TI - Peripheral artery disease, biomarkers, and darapladib JO - Am Heart J VL - 161 UR - https://doi.org/10.1016/j.ahj.2011.01.017 DO - 10.1016/j.ahj.2011.01.017 ID - Berger2011 ER - TY - JOUR AU - Serruys, P. W. AU - Garcia-Garcia, H. M. AU - Buszman, P. AU - Erne, P. AU - Verheye, S. AU - Aschermann, M. PY - 2008 DA - 2008// TI - Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque JO - Circulation VL - 118 UR - https://doi.org/10.1161/CIRCULATIONAHA.108.771899 DO - 10.1161/CIRCULATIONAHA.108.771899 ID - Serruys2008 ER - TY - JOUR AU - Hu, M. M. AU - Zhang, J. AU - Wang, W. Y. AU - Wu, W. Y. AU - Ma, Y. L. AU - Chen, W. H. PY - 2011 DA - 2011// TI - The inhibition of lipoprotein-associated phospholipase A2 exerts beneficial effects against atherosclerosis in LDLR-deficient mice JO - Acta Pharmacol Sin VL - 32 UR - https://doi.org/10.1038/aps.2011.127 DO - 10.1038/aps.2011.127 ID - Hu2011 ER - TY - JOUR AU - Wilensky, R. L. AU - Shi, Y. AU - Mohler, E. R. AU - Hamamdzic, D. AU - Burgert, M. E. AU - Li, J. PY - 2008 DA - 2008// TI - Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development JO - Nat Med VL - 14 UR - https://doi.org/10.1038/nm.1870 DO - 10.1038/nm.1870 ID - Wilensky2008 ER - TY - JOUR AU - Davidson, M. H. AU - Corson, M. A. AU - Alberts, M. J. AU - Anderson, J. L. AU - Gorelick, P. B. AU - Jones, P. H. PY - 2008 DA - 2008// TI - Consensus panel recommendation for incorporating lipoprotein-associated phospholipase A2 testing into cardiovascular disease risk assessment guidelines JO - Am J Cardiol VL - 101 UR - https://doi.org/10.1016/j.amjcard.2008.04.019 DO - 10.1016/j.amjcard.2008.04.019 ID - Davidson2008 ER - TY - JOUR AU - White, H. D. AU - Held, C. AU - Stewart, R. AU - Tarka, E. AU - Brown, R. AU - Davies, R. Y. PY - 2014 DA - 2014// TI - Darapladib for preventing ischemic events in stable coronary heart disease JO - N Engl J Med VL - 370 UR - https://doi.org/10.1056/NEJMoa1315878 DO - 10.1056/NEJMoa1315878 ID - White2014 ER - TY - JOUR AU - O’Donoghue, M. L. AU - Braunwald, E. AU - White, H. D. AU - Steen, D. P. AU - Lukas, M. A. AU - Tarka, E. PY - 2014 DA - 2014// TI - Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial JO - JAMA VL - 312 UR - https://doi.org/10.1001/jama.2014.11061 DO - 10.1001/jama.2014.11061 ID - O’Donoghue2014 ER - TY - JOUR AU - Cai, A. AU - Zheng, D. AU - Qiu, R. AU - Mai, W. AU - Zhou, Y. PY - 2013 DA - 2013// TI - Lipoprotein-associated phospholipase A2 (Lp-PLA(2)): a novel and promising biomarker for cardiovascular risks assessment JO - Dis Markers VL - 34 UR - https://doi.org/10.1155/2013/432136 DO - 10.1155/2013/432136 ID - Cai2013 ER - TY - JOUR AU - Wilensky, R. L. AU - Macphee, C. H. PY - 2009 DA - 2009// TI - Lipoprotein-associated phospholipase A(2) and atherosclerosis JO - Curr Opin Lipidol VL - 20 UR - https://doi.org/10.1097/MOL.0b013e3283307c16 DO - 10.1097/MOL.0b013e3283307c16 ID - Wilensky2009 ER - TY - JOUR AU - Daida, H. AU - Iwase, T. AU - Yagi, S. AU - Ando, H. AU - Nakajima, H. PY - 2013 DA - 2013// TI - Effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity in Japanese dyslipidemic patients, with exploratory analysis of a PLA2G7 gene polymorphism of Val279Phe JO - Circ J VL - 77 UR - https://doi.org/10.1253/circj.CJ-12-0813 DO - 10.1253/circj.CJ-12-0813 ID - Daida2013 ER - TY - JOUR AU - Yang, E. H. AU - McConnell, J. P. AU - Lennon, R. J. AU - Barsness, G. W. AU - Pumper, G. AU - Hartman, S. J. PY - 2006 DA - 2006// TI - Lipoprotein-associated phospholipase A2 is an independent marker for coronary endothelial dysfunction in humans JO - Arterioscler Thromb Vasc Biol VL - 26 UR - https://doi.org/10.1161/01.ATV.0000191655.87296.ab DO - 10.1161/01.ATV.0000191655.87296.ab ID - Yang2006 ER - TY - JOUR AU - Lavi, S. AU - McConnell, J. P. AU - Rihal, C. S. AU - Prasad, A. AU - Mathew, V. AU - Lerman, L. O. PY - 2007 DA - 2007// TI - Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: association with early coronary atherosclerosis and endothelial dysfunction in humans JO - Circulation VL - 115 UR - https://doi.org/10.1161/CIRCULATIONAHA.106.671420 DO - 10.1161/CIRCULATIONAHA.106.671420 ID - Lavi2007 ER - TY - JOUR AU - Iwase, M. AU - Sonoki, K. AU - Sasaki, N. AU - Ohdo, S. AU - Higuchi, S. AU - Hattori, H. PY - 2008 DA - 2008// TI - Lysophosphatidylcholine contents in plasma LDL in patients with type 2 diabetes mellitus: relation with lipoprotein-associated phospholipase A2 and effects of simvastatin treatment JO - Atherosclerosis VL - 196 UR - https://doi.org/10.1016/j.atherosclerosis.2007.02.012 DO - 10.1016/j.atherosclerosis.2007.02.012 ID - Iwase2008 ER - TY - JOUR AU - Papathanasiou, A. I. AU - Lourida, E. S. AU - Tsironis, L. D. AU - Goudevenos, J. A. AU - Tselepis, A. D. PY - 2008 DA - 2008// TI - Short- and long-term elevation of autoantibody titers against oxidized LDL in patients with acute coronary syndromes. Role of the lipoprotein-associated phospholipase A2 and the effect of atorvastatin treatment JO - Atherosclerosis VL - 196 UR - https://doi.org/10.1016/j.atherosclerosis.2006.10.033 DO - 10.1016/j.atherosclerosis.2006.10.033 ID - Papathanasiou2008 ER - TY - JOUR AU - Kolodgie, F. D. AU - Burke, A. P. AU - Skorija, K. S. AU - Ladich, E. AU - Kutys, R. AU - Makuria, A. T. PY - 2006 DA - 2006// TI - Lipoprotein-associated phospholipase A2 protein expression in the natural progression of human coronary atherosclerosis JO - Arterioscler Thromb Vasc Biol VL - 26 UR - https://doi.org/10.1161/01.ATV.0000244681.72738.bc DO - 10.1161/01.ATV.0000244681.72738.bc ID - Kolodgie2006 ER -