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Table 1 Composition of experimental diets for control (gavaged with saline) or treatment guinea pigs (gavaged with A-002).

From: A-002 (Varespladib), a phospholipase A2inhibitor, reduces atherosclerosis in guinea pigs

 

g/100 g

% Energy

Soybean protein

22.5

23

Carbohydrate

40.5

35

Fat mix a

15.1

42

Cellulose

10.0

 

Guar gum

2.5

 

Mineral Mix b

8.2

 

Vitamin Mix b

1.1

 

Cholesterol

0.25

 
  1. aThe fat mix was high in lauric and myristic acids known to cause endogenous hypercholesterolemia in guinea pigs.
  2. bMineral and vitamin mix are formulated to meet NRC requirements for guinea pigs.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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