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Table 2 Mortality relative to studied variables including information derived from exploratory analysis (Cox proportional hazards model)

From: Beta-2 adrenergic receptor gene polymorphisms Gln27Glu, Arg16Gly in patients with heart failure

Variables p Hazard ratio 95% Confidence interval
Serum sodium < 0.001 0.94 (0.91; 0.96)
Serum creatinine < 0.001 1.47 (1.27; 1.69)
Etiology 0.09 0.91 (0.81; 1.02)
Ethnicity 0.73 0.97 (0.80; 1.17)
Gln27Glu # 0.01 5.48 (1.50; 20.08)
Age < 0.001 1.03 (1.02; 1.05)
Age * Gln27Glu # 0.004 0.97 (0.95; 0.99)
Baseline beta-blocker use 0.001 2.30 (1.43; 3.71)
  1. # dominant model (GlnGln genotype reference versus GlnGlu + GluGlu genotypes)
  2. Serum sodium, serum creatinine and age included as continuous variables
  3. Etiology (1. Chagasic, 2 Idiopathic, 3 Hypertensive, 4 Isquemic, 5 Heart failure due to valve disease)