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Table 2 Echocardiographic data in postischemic and overpacing models

From: Cardiac insulin-like growth factor-1 and cyclins gene expression in canine models of ischemic or overpacing cardiomyopathy

 

Infarct

Paced

Echocardiographic indices

Baseline

End

Baseline

End

LVEF,%

68 ± 3

55.5 ± 3 §

66 ± 2

35 ± 2 *

FS, %

37 ± 2

33 ± 1

36 ± 1

17 ± 1 *

LV mass, g

92 ± 4

118 ± 8 ‡

126 ± 7

127 ± 6

IVSd, mm

7.1 ± 0.2

8 ± 0.3

7 ± 0.2

6 ± 0.3 §

IVSs, mm

11.2 ± 0.4

12 ± 0.8

11 ± 0.6

6 ± 0.3 *

LVDd, mm

36.5 ± 0.5

42 ± 2 §

39 ± 1.5

50 ± 2 *

LVDs, mm

23 ± 1

28 ± 1 §

25 ± 1

41 ± 1 *

LVFWd, mm

8 ± 0.3

7.2 ± 0.5

7.8 ± 0.4

6.5 ± 0.3 ‡

LVFWs, mm

12 ± 0.3

10 ± 0.7 ‡

12 ± 0.5

9.6 ± 0.4 §

RWT

0.4 ± 0.02

0.4 ± 0.02

0.4 ± 0.02

0.2 ± 0.02 *

LVEDV, ml

56 ± 2

81 ± 8 §

66 ± 6

117 ± 9 *

LVESV, ml

18 ± 2

32 ± 4 §

22 ± 2

76 ± 6 *

IVSFT, %

58 ± 7

48 ± 6

49 ± 9

14 ± 4 §

LVFWFT, %

53 ± 4

40 ± 5 ‡

56 ± 3

40 ± 5 ‡

  1. LVEF, left ventricular ejection fraction; FS, fractional shortening; LVmass, left ventriular mass; IVSd, interventricular septum thickness in diastole; IVSs, interventricular septum thickness in systole; LVDd, left ventricular diameter in diastole; LVDs, left ventricular diameter in systole; LVPWd, left ventricular posterior wall diameter in diastole; LVPWs, left ventricular posterior wall diameter in systole; RWT, relative wall thickness; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; IVSFT, interventricular septum fractional thickening; LVFWFT, left ventricular free wall fractional thickening. ‡ p < 0.05, § p < 0.01, * p < 0.001 in each end group versus baseline.