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Figure 6 | BMC Cardiovascular Disorders

Figure 6

From: Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells

Figure 6

HIF-1α promotes Bax activation in HK-2 cells. Cells were subjected to normoxia or hypoxia of 16 h after sorting in a flow cytometer. Active and Total Bax protein expression of the whole cell lysates of EGFP positive cells is shown of cells transfected with either pEGFP or pEGFP and pcDNA3-HA-Hif-1α or pcDNA3-DN-Hif-1α. N = Normoxia; H = Hypoxia. Data shown is representative of two separate experiments.

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