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Figure 2 | BMC Cardiovascular Disorders

Figure 2

From: The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

Figure 2

Power estimates for the CoLaus study. Power for various sample sizes in unmatched case-control studies. Arbitrary allelic frequency of 0.3, a disease prevalence of 50% and a type 1 error rate of 10-7taking into account 500'000 genetics markers. Curves are for estimated genetic effects (odds ratios) of 1.2 to 1.8. The numbers of cases for main CVRFs in the CoLaus study are: Hypertension: 2268. Dyslipidemia: 2021. Obesity: 963. Smoking (> 25 cigarettes/day): 746. Type 2 diabetes: 398. Coronary heart disease: 262. Low HDL: 170.

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