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Table 2 Biochemical and haematological characteristics of individual with differential genotype of WRN

From: WRN polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts

Genotype of WRN

1367CC/1074FF

1367CR/1074LL

1367RR/1074FL

1367RR/1074LL

P value

n

25

12

 

Fibrinogen (mg/dl)

200.92 ± 7.04

204.81 ± 8.9

0.077

CRP (mg/l)

0.8 ± 0.012

0.8 ± 0.063

0.5

RBC (106/mm3)

4.832 ± 0.206

4.543 ± 0.24

0.139

Creatinine (mg/dl)

0.92 ± 0.056

0.93 ± 0.026

0.458

WBC (106/mm3)

0.69 ± 0.008

0.73 ± 0.05

0.283

PAI-1 (ng/ml)

16.09 ± 1.206

7.56 ± 1.45

0.031

  1. Values are shown as mean ± standard error of the mean. CRP = C reactive protein, RBC = red blood cells, WBC = white blood cells, PAI-1 = plasminogen activator inhibitor type 1. The differences between groups were analyzed by paired Student's test