Table 1 Studies of cost-effectiveness of AAA screening
From: Is population screening for abdominal aortic aneurysm cost-effective?
Nr. | Study | Alternative programs | ICER* | Comments |
|---|---|---|---|---|
1 | MASS 2002 (UK) [8] | Screening of men aged 65–74 years vs. no systematic screening strategy | GBP 28 400 per gained life-year or GBP 36 000 per QALY Price level: year 2000 | Costs outside the health care sector not included. Different discount rates used for costs and effects. QOL after elective surgery assumed to be similar to normal population. |
2 | Kim et al. 2008 (UK) [9] | Screening of men aged 65–74 years vs. no systematic screening strategy | USD 19 500 per gained life-year Price level: year 2004–05 | Only short-term hospital costs included. QOL after elective surgery assumed to be similar to normal population. |
3 | Lindholt et al. 2006 (DK) [10] | Screening of males aged 65–73 years vs. no systematic screening strategy | GBP 6 090 per gained life-year or GBP 10 793 per saved life Price level: year 2004 | Only short-term hospital costs included. Costs and health effects not discounted. |
4 | Wilmink et al. 2003 (UK) [11] | Screening of males aged >50 years vs. no systematic screening strategy | USD 1 173 per gained life-year Price level: year 1995 | Only short-term hospital costs included. Costs and health effects not discounted. |
5 | Hobbs et al. 2004 (UK) [12] | Screening of males aged >50 years vs. no systematic screening strategy | GBP 375–655 per gained life-year Price level: year? | Only short-term hospital costs included. Costs and health effects not discounted. |
6 | Ishikawa et al. 2004 (JP) [13] | Screening of males and females aged >60 years vs. no systematic screening strategy | USD 2 366 per detected AAA Price level: year? | Only short-term hospital costs included. Costs and health effects not discounted. |
7 | Lindholt et al. 2002 (DK) [14] | Screening of males aged 65–73 years vs. no systematic screening strategy | DKK 7 540 per gained life-year or DKK 67 855 per saved life Price level: year 1998 | Only short-term hospital costs included. Costs and health effects not discounted. Long-term survival after elective surgery is assumed to be similar to normal population. Data for males aged 65–73 years are used as estimates for 65-year-old males. |
8 | Soisalon et al. 2001 (FI) [15] | Screening of first-degree relatives vs. no systematic screening strategy | USD 6 200 per gained life-year Price level: year 1987–89 | Targeted screening of familial AAA. Only hospital costs included. |
9 | Kim et al. 2007 (UK) [16] | Screening of males aged 65 years vs. no systematic screening strategy | GBP 510 per gained life-year or GBP 676 per QALY Price level: year 2000 | Only short-term hospital costs included. Long-term survival and QOL after elective surgery is assumed to be similar to normal population. Data for males aged 65–74 years used as estimates for 65-year-old males. |
10 | Wanhainen et al. 2005 (SE) [17] | Screening of males at age 60, 65 or 70 years vs. no systematic screening strategy | USD 10 474 per gained life-year or USD 13 900 per QALY (results for +65 year old) Price level: year 2003 | Only short-term hospital costs and costs of lost time and travelling due to screening included. QOL after elective surgery assumed to be similar to normal population. Data for males aged 65–74 years (pooled estimates from heterogeneous studies) used as estimates for 65-year-old males. |
11 | Henrikson et al. 2005 (SE) [18] | Screening of men aged 65 years vs. no systematic screening strategy | EUR 7 760 per gained life-year or EUR 9,700 per QALY Price level: year 2003 | QOL after elective surgery assumed to be similar to normal population. Data for males aged 65–74 years (pooled estimates from heterogeneous studies) used as estimates for 65-year-old males. |
12 | Boll et al. 2003 (NL) [19] | Screening of males aged 60–65 years vs. no systematic screening strategy | EUR 1 176 per gained life-years Price level: year 1997 | Only short-term hospital costs included. Long-term survival after elective surgery assumed to be similar to normal population. |
13 | Lee et al. 2002 (US) [20] | Screening of males aged 70 years vs. no systematic screening strategy | USD 11 215 per QALY Price level: year? | Only short-term hospital costs included. Long-term survival and QOL after elective surgery assumed to be similar to normal population. |
14 | Conelly et al. 2002 (CA) [21] | Screening of males and females aged >50 years vs. no systematic screening strategy | CAD 741 per QALY Price level: year? | Only short-term hospital costs included. Long-term survival and QOL after elective surgery assumed to be similar to normal population. |
15 | Montreuil et al. 2008 (CA) [22] | Screening of males aged 65 years vs. no systematic screening strategy | CAD 6 194 per QALY Price level: year 2005 | Only short-term hospital costs included. QOL after elective surgery assumed to be similar to normal population. Data for males aged 65–74 years used as estimates for 65-year-old males. |
16 | Silverstein et al. 2005 (US) [23] | Screening of males at age 65 years vs. no systematic screening strategy | USD 19 720 per QALY Price level: year? | Only short-term hospital costs included. Long-term survival and QOL after elective surgery assumed to be similar to normal population. Data for males aged 65–74 years used as estimates for 65-year-old males. |