Table 3 Blood results at baseline and follow-up
| Â | Baseline | Post-treatment | Adjusted mean treatment difference | p-value | ||
|---|---|---|---|---|---|---|
| Â | Placebo (n = 79) | Vitamins (n = 83) | Placebo (n = 79) | Vitamins (n = 83) | Â | Â |
tHcy μmol/L | 11.7 (10.9, 12.6) | 10.3 (9.6, 11.1) | 11.8 (10.9, 12.8) | 7.9 (7.5, 8.4) | -3.7 ± 0.8 | < 0.001 |
Serum B 6 nmol/L | 40 (36, 45) | 34 (31, 38) | 34 30, 38) | 118 (116, 121) | 79 ± 3 | < 0.001 |
Serum B 12 pmol/L | 297 (266, 331) | 317 (285, 351) | 274 (248, 302) | 638 (600, 680) | 328 ± 25 | < 0.001 |
RBC folate nmol/L | 805 (732, 885) | 884 (796, 982) | 944 (839, 1061) | 2534 (2401, 2673) | 1475 ± 103 | < 0.001 |
Cholesterol mmol/L | 4.7 (4.5, 4.9) | 4.8 (4.6, 5.0) | 4.3 (4.2, 4.5) | 4.4 (4.2, 4.6) | -0.1 ± 0.2 | 0.63 |
Triglycerides mmol/L | 1.4 (1.2, 1.5) | 1.5 (1.3, 1.6) | 1.3 (1.1, 1.4) | 1.3 (1.1, 1.4) | -0.1 ± 0.1 | 0.53 |
LDL* mmol/L | - | - | 2.3 (2.1, 2.4) | 2.3 (2.1, 2.4) | - | - |
HDL mmol/L | - | - | 1.3 (1.2, 1.4) | 1.3 (1.2, 1.3) | - | - |
Creatinine μmol/L | 80 (76, 83) | 79 (74, 84) | 84 (81, 88) | 88 (83, 90) | 3.1 ± 3.0 | 0.30 |
Cystatin C mg/L | 1.02 (0.97, 1.07) | 1.05 (1.00, 1.11) | 1.04 (0.99, 1.09) | 1.08 (1.02, 1.15) | 0.01 ± 0.03 | 0.69 |
GGT mmol/L | - | - | 26 (22, 30) | 30 (27, 34) | - | - |
Glucose mmol/L | 5.4 (5.3, 5.6) | 5.5 (5.3, 5.7) | 5.1 (4.9, 5.2) | 5.2 (5.0, 5.4) | 0.1 ± 0.2 | 0.59 |
HbA1c % | - | - | 5.8 (5.6, 6.0) | 5.9 (5.7, 6.1) | - | - |