| Baseline | Follow-up | ||
---|---|---|---|---|
 | Placebo (n = 79) | Vitamins (n = 83) | Placebo (n = 79) | Vitamins (n = 83) |
Age (years) | 65 ± 11 | 64 ± 12 | 69 ± 11 | 68 ± 12 |
Sex (male) | 56 (71) | 61 (73) | 56 (71) | 61 (73) |
Treatment period (years) | - | - | 3.8 ± 0.9 | 4.0 ± 0.9 |
Stroke type | Â | Â | Â | Â |
Ischemic | 54 (69) | 62 (75) | - | - |
TIA | 19 (24) | 13 (16) | - | - |
Haemorrhagic | 4 (5) | 8 (10) | - | - |
Unknown | 2 (3) | 0 (0) | - | - |
Medications | Â | Â | Â | Â |
Antiplatelet agent | 68 (86) | 63 (76) | 60 (76) | 59 (71) |
Warfarin | 11 (14) | 16 (19) | 13 (17) | 15 (18) |
Statin | 24 (32) | 30 (36) | 59 (75) | 56 (68) |
Antihypertensive agent | 47 (60) | 45 (54) | 69 (87) | 71 (86) |
Risk factors | Â | Â | Â | Â |
Hypertension* | 57 (72) | 63 (75) | 69 (87) | 71 (86) |
Hypercholesterolemia†| 25 (32) | 29 (35) | 59 (75) | 56 (68) |
Diabetes‡ | 14 (18) | 15 (18) | 22 (28) | 19 (23) |
Current smoker | 15 (19) | 18 (22) | 7 (9) | 7 (8) |
Fruit (pieces/day) | - | - | 1.7 ± 1.3 | 1.6 ± 1.1 |
Vegetables (serves/day) | - | - | 3.5 ± 1.1 | 3.5 ± 1.2 |
Clinical characteristics | Â | Â | Â | Â |
BMI (kg/m2) | - | - | 29.3 ± 4.9 | 29.1 ± 4.8 |
Waist circumference (cm) | - | - | 103 ± 12 | 103 ± 13 |
Systolic BP (mmHg) | 135 ± 15 | 132 ± 16 | 145 ± 19 | 140 ± 16 |
Diastolic BP (mmHg) | 78 ± 9 | 78 ± 10 | 79 ± 11 | 78 ± 10 |
GFR (ml/min/1.73 m2)§ | 84 ± 19 | 88 ± 21 | 79 ± 18 | 77 ± 24 |