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Table 2 Subject characteristics at baseline and follow-up

From: The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis

 

Baseline

Follow-up

 

Placebo (n = 79)

Vitamins (n = 83)

Placebo (n = 79)

Vitamins (n = 83)

Age (years)

65 ± 11

64 ± 12

69 ± 11

68 ± 12

Sex (male)

56 (71)

61 (73)

56 (71)

61 (73)

Treatment period (years)

-

-

3.8 ± 0.9

4.0 ± 0.9

Stroke type

    

Ischemic

54 (69)

62 (75)

-

-

TIA

19 (24)

13 (16)

-

-

Haemorrhagic

4 (5)

8 (10)

-

-

Unknown

2 (3)

0 (0)

-

-

Medications

    

Antiplatelet agent

68 (86)

63 (76)

60 (76)

59 (71)

Warfarin

11 (14)

16 (19)

13 (17)

15 (18)

Statin

24 (32)

30 (36)

59 (75)

56 (68)

Antihypertensive agent

47 (60)

45 (54)

69 (87)

71 (86)

Risk factors

    

Hypertension*

57 (72)

63 (75)

69 (87)

71 (86)

Hypercholesterolemia†

25 (32)

29 (35)

59 (75)

56 (68)

Diabetes‡

14 (18)

15 (18)

22 (28)

19 (23)

Current smoker

15 (19)

18 (22)

7 (9)

7 (8)

Fruit (pieces/day)

-

-

1.7 ± 1.3

1.6 ± 1.1

Vegetables (serves/day)

-

-

3.5 ± 1.1

3.5 ± 1.2

Clinical characteristics

    

BMI (kg/m2)

-

-

29.3 ± 4.9

29.1 ± 4.8

Waist circumference (cm)

-

-

103 ± 12

103 ± 13

Systolic BP (mmHg)

135 ± 15

132 ± 16

145 ± 19

140 ± 16

Diastolic BP (mmHg)

78 ± 9

78 ± 10

79 ± 11

78 ± 10

GFR (ml/min/1.73 m2)§

84 ± 19

88 ± 21

79 ± 18

77 ± 24

  1. Values are mean ± standard deviation or number (%)
  2. TIA indicates transient ischemic attack of eye or brain; BMI, body mass index; BP, blood pressure, GFR, glomerular filtration rate.
  3. *History of previous or current hypertension
  4. †Treated for hypercholesterolaemia
  5. ‡ Includes type I, type II and impaired fasting glycaemia
  6. §Estimated using the Modification of Diet in Renal Disease Study equation [50]