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Figure 4 | BMC Cardiovascular Disorders

Figure 4

From: Up-regulation of endothelin type B receptors in the human internal mammary artery in culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways

Figure 4

(A) The levels of endothelin ET B receptor mRNA expression in human internal mammary arteries, examined using real time PCR. (B) Endothelin ETB receptor protein expression in human internal mammary arteries, examined using Western blot. The arteries were either not cultured or cultured in the absence or presence of the protein kinase C inhibitors Ro-32-0432 or bisindolylmaleimide I. The results are shown as mean values ± S.E.M of six experiments. Endothelin ETB mRNA levels in cultured and non-cultured arteries were compared using Student's t-test, where P < 0.05 (*) was considered significant.

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