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Table 1 Baseline characteristics in 77 rheumatoid arthritis patients. Values are mean [95% CI] or n (%).

From: Aminotransferases are associated with insulin resistance and atherosclerosis in rheumatoid arthritis

Characteristic All patients (n = 77) Patients with plaque (n = 25) Patients without plaque (n = 52) p
Age (years) 54 [51–56] 60 [57–63] 51 [48–54] 0.0002
Women 64 (83) 21 (84) 43 (83) 0.9
Caucasian: Asian 69 (90): 8 (10) 23 (92): 2 (8) 46 (88): 6 (12) 0.6
Life style factors     
   Current smokers 17 (22) 8 (32) 9 (17) 0.2
   Current smoking (cigarettes/day)* 0.8 [0.4–1.4] 1.5 [0.4–3.3] 0.6 [0.2–1.2] 0.2
   Current alcohol users 26 (34) 9 (36) 17 (33) 0.8
   Current alcohol (units/week)* 1 [0.6–1.6] 1.2 [0.4–2.6] 1.0 [0.4–1.7] 0.7
   Current exercisers 22 (29) 6 (25) 16 (31) 0.6
   Exercise (hours/week)* 0.5 [0.3–0.8] 0.4 [0.1–0.9] 0.6 [0.3–0.9] 0.6
Disease duration (years)* 6.6 [4.9–8.7] 9.2 [5.6–15.2] 5.6 [4.0–7.8] 0.1
Rheumatoid factor positive 61 (79) 19 (76) 42 (81) 0.6
Acute phase reactants     
   Hs-C-reactive protein (mg/l)* 7.4 [5.4–10.2] 9.4 [5.8–15.2] 6.7 [4.3–10.2] 0.3
   ESR (mm/hr)* 14 [10–18] 11 [7–17] 15 [10–21] 0.3
Other cardiovascular risk factors     
   Waist circumference (cm) 86 [83–88] 88 [83–93] 85 [81–88] 0.3
   Body mass index (kg/m2) 24.4 [23.4–25.3] 24.2 [22.8–26.0] 24.3 [23.1–25.6] 0.9
   Hypertension 34 (44) 19 (76) 15 (29) 0.0002
   Systolic blood pressure (mmHg) 127 [124–131] 131 [124–138] 125 [121–129] 0.1
   Diastolic blood pressure (mmHg) 82 [80–84] 81 [78–85] 82 [80–85] 0.6
   Total cholesterol (mmol/l) 5.1 [4.9–5.3] 5.0 [4.6–5.3] 5.1 [4.9–5.4] 0.5
   LDL cholesterol (mmol/l) 2.9 [2.7–3.0] 2.8 [2.5–3.1] 2.9 [2.7–3.1] 0.5
   HDL cholesterol (mmol/l) 1.6 [1.5–1.7] 1.7 [1.5–1.9] 1.6 [1.5–1.7] 0.5
   Triglycerides (mmol/l)* 1.1 [1.0–1.2] 1.2 [1.0–1.4] 1.0 [0.9–1.1] 0.08
   HOMA-IR (uU.mmol/ml.l)* 1.15 [1.02–1.29] 1.45 [1.18–1.77] 1.03 [0.90–1.19] 0.009
   Glucose (mmol/l) 4.3 [4.2–4.5] 4.3 [4.2–4.5] 4.5 [4.2–4.5] 0.8
   Diabetes 3 (4) 0 (0) 3 (6) 0.3
   Hypothyroidism 19 (25) 10 (40) 9 (17) 0.03
Framingham score* 4 [4–5] 6 [5–8] 4 [3–5] 0.009
CCA intima-media thickness (mm) 0.65 [0.63–0.68] 0.73 [0.69–0.78] 0.62 [0.60–0.64] 0.0001
  1. CI, confidence interval; Hs, high sensitivity; ESR, erythrocyte sedimentation rate; LDL, low density lipoprotein; HDL, high density lipoprotein; HOMA-IR, homeostasis model assessment of insulin resistance; CCA, common carotid artery.
  2. *Variables for which geometric means [95% CI] are given. For comparison of characteristics between patients with plaque and patients without plaque.