Figure 1From: Sirolimus inhibits key events of restenosis in vitro/ex vivo: evaluation of the clinical relevance of the data by SI/MPL- and SI/DES-ratio'sThe effects of SRL (0.01, 0.1, 1, 10, 100, 1000 ng/ml) on TNF-α induced expression of ICAM-1 are demonstrated. A dose dependent significant inhibition of ICAM-1 expression was detected in HCAEC (SRL ≥ 0.01 ng/ml), HUVEC (SRL ≥ 1 ng/ml), and HCMSMC (SRL ≥ 10 ng/ml).Back to article page