Figure 6

Macrophages and neutrophils in apoB100 transgenic mice on high fat diet: (A) & (B) Tissue sections of arterial blood vessels in the heart were immunolabeled with the antibody to F4/80 which is specific to macrophages, and (C) & (D) with an antibody to myeloperoxidase to detect neutrophils. Macrophages were observed in the walls of arterial vessels in mice exposed to SSW smoke but not in the control mice. However, neutrophils were not found in the arterial vessel walls of either control mice or mice exposed to SSW. The mice were exposed to SSW for 1 year as described in the Materials and Methods. Representative images of one mouse out of three.