Figure 3From: Human antimicrobial peptide LL-37 is present in atherosclerotic plaques and induces death of vascular smooth muscle cells: a laboratory study Caspase-3 activity in cultured vascular smooth muscle cells. Cells were incubated for 1, 3 or 7 hours in the presence of LL-37 at 10 (●) or 30 (■) μg/ml. A significant increase in caspase-3 activity was observed in cells incubated for 1, 3 and 7 hours with LL-37 at 30 μg/ml (n = 6, *P < 0.05, one way repeated measures ANOVA followed by Holm-Sidak test). Values are means + or - S.E.M.Back to article page