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Figure 1 | BMC Cardiovascular Disorders

Figure 1

From: Mitochondrial oxidative stress and nitrate tolerance – comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD+/-mice

Figure 1

Vasodilator responses of isolated aortic vessel segments upon chronic treatment of wild type and Mn-SOD +/- mice with GTN or PETN. (A) Concentration-relaxation curves for GTN (10-9 to 10-4.5 M) in vessels from wild type and Mn-SOD+/- mice upon treatment with ethanol or GTN in ethanol. The symbols are closed circles (ethanol infused wild type), closed triangles (GTN infused wild type), open circles (ethanol infused Mn-SOD+/-) and open triangles (GTN infused Mn-SOD+/-). Data are mean ± SEM of 7–10 independent experiments. (B) Concentration-relaxation curves for PETN (10-10 to 10-4.5 M) in vessels from wild type and Mn-SOD+/- mice upon treatment with DMSO or PETN in DMSO. The symbols are closed circles (DMSO infused wild type), closed triangles (PETN infused wild type), open circles (DMSO infused Mn-SOD+/-) and open triangles (PETN infused Mn-SOD+/-). Data are mean ± SEM of 6–8 independent experiments.

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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