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Figure 2 | BMC Cardiovascular Disorders

Figure 2

From: Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1

Figure 2

Effects of ER ligands on TFPI production in HCAEC. The cells were incubated in the absence (controls) or presence of 10 nM each of E2, EE2, raloxifene (RAL), tamoxifen (TAM) or fulvestrant (FUL). The bars show TFPI in the media (black bars), in whole cell lysates (white bars), or in the media after concurrent treatment with 1000 nM fulvestrant (gray bars) and indicate percent change (mean ± SD) compared to controls. Results are from three independent experiments. * is p ≤ 0.05. §refers to comparisons between respective gray and black bars, where §ns is non significant difference and §* is p ≤ 0.01

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