Table 2 Genes included in cluster 3. Genes are presented by their Affymetrix identification code (Affy ID), gene name, gene symbol and GO cellular component classification. The mean signals from the DNA microarray analysis from the three patients during the time-points in thehistopathological sequence (before, during and after rejection) are presented. Two probe sets detecting the STAT1 and HLA-C genes are included in the cluster.
From: Evaluation of CXCL9 and CXCL10 as circulating biomarkers of human cardiac allograft rejection
Affy ID | Gene name | Gene symbol | GO cell component | Mean microarray signal | ||
|---|---|---|---|---|---|---|
Before | During | After | ||||
200887_s_at | Signal transducer and activator of transcription 1, 91 kDa | STAT1 | Nucleus, cytoplasm | 723 | 1185 | 719 |
201508_at | Insulin-like growth factor binding protein 4 | IGFBP4 | Extracellular | 352 | 664 | 407 |
201762_s_at | Proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | PSME2 | Proteasome activator complex | 370 | 598 | 424 |
202269_x_at | Guanylate binding protein 1, interferon-inducible, 67 kDa | GBP1 | ---- | 224 | 438 | 237 |
203915_at | Chemokine (C-X-C motif) ligand 9 | CXCL9 | Extracellular | 57 | 1106 | 250 |
204070_at | Retinoic acid receptor responder (tazarotene induced) 3 | RARRES3 | ---- | 122 | 425 | 175 |
204533_at | Chemokine (C-X-C motif) ligand 10 | CXCL10 | Extracellular | 103 | 589 | 184 |
204806_x_at | Major histocompatibility complex, class I, F | HLA-F | ---- | 530 | 1040 | 634 |
208451_s_at | Complement component 4A | C4A | Extracellular | 260 | 589 | 295 |
209957_s_at | Natriuretic peptide precursor A | NPPA | Extracellular | 1041 | 2780 | 1024 |
211799_x_at | Major histocompatibility complex, class I, C | HLA-C | Integral to membrane | 301 | 670 | 372 |
214459_x_at | Major histocompatibility complex, class I, C | HLA-C | Integral to membrane | 2157 | 3655 | 2553 |
216187_x_at | Homo sapiens Alu repeat (LNX1) mRNA sequence | ---- | ---- | 472 | 832 | 551 |
217436_x_at | Major histocompatibility complex, class I, J | HLA-J | Integral to membrane | 231 | 517 | 299 |
217767_at | Complement component 3 | C3 | Extracellular | 338 | 531 | 310 |
HUM-ISGF3A_3_at | Signal transducer and activator of transcription 1, 91 kDa | STAT1 | Nucleus, cytoplasm | 390 | 665 | 357 |