Circadian rhythm of the autonomic nervous system in insulin resistant subjects with normoglycemia, impaired fasting glycemia, impaired glucose tolerance, type 2 diabetes mellitus

Table 2 Time domain measures for each insulin resistant group and control group.

	NGR	IFG	IGT	DM	Controls	P (ANOVA)
SDNN (ms)	130,9 ± 35,9*	117,9 ± 24,2*	103,1 ± 37,0,*	89,6 ± 30,3,*	176,6 ± 29,5	< 0,001
SDNN day (ms)	105,2 ± 28,3	109,4 ± 31,7	81,1 ± 18,6,*	77,3 ± 23,5 ,*	120,2 ± 26,9	< 0,001
SDNN night (ms)	118,8 ± 46,1	71,9 ± 11,8,*	77,2 ± 32,0,*	69,0 ± 22,1,*	119,5 ± 38,2	< 0,001
RMS-SD (msec)	43,15 ± 20,33	35,16 ± 10,06	27,19 ± 12,46**	32,78 ± 15,51**	36,75 ± 10,59	0,032
RMS-SD day (msec)	41,58 ± 18,14*	34,46 ± 10,47	23,93 ± 11,41**	32,34 ± 14,46**	31,37 ± 9,07	0,007
RMS-SD night (msec)	47,47 ± 29,26	36,78 ± 11,01*	30,76 ± 15,34,*	32,43 ± 15,51,*	47,47 ± 17,60	0,013

Results are expressed as mean ± SD for each group. P < .05 was chosen to be the threshold of statistical significance for ANOVA and LSD post hoc test. SDNN: standard deviation of all sinus rhythm RR intervals ms, RMS SD: the square root of the mean of the sum of the squares of differences between adjacent NN intervals, NGR: normal glucose regulation, IFG: impaired fasting glycemia, IGT: impaired glucose tolerance, DM: type 2 diabetes.
* P < .01 for comparison with control group.
** P < .05 for comparison with NGR grou

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