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Table 6 Association of combinations of sero-positivity to Chlamydia pneumoniae (CP), chlamydia heat shock protein (ch-hsp)60 with history of diabetes and secondary fatal and non-fatal CVD events during follow up: Results of a multivariate analysis

From: Chlamydia pneumoniae, heat shock proteins 60 and risk of secondary cardiovascular events in patients with coronary heart disease under special consideration of diabetes: a prospective study

  HR (95% CI)
  Crude Partially adjusted a Fully adjusted b
Combination of CP (IgA) and history of diabetes    
CP (IgA) neg. and diabetes neg. 1ref 1ref 1ref
CP (IgA) neg. and diabetes pos. 2.41 (1.21–4.80) 2.31 (1.16–4.61) 2.16 (1.08–4.33)
CP (IgA) pos. and diabetes neg. 1.64 (0.92–2.90) 1.63 (0.93–2.90) 1.60 (0.89–2.87)
CP (IgA) pos. and diabetes pos. 3.20 (1.61–6.38) 3.04 (1.51–6.12) 2.63 (1.29–5.36)
Combination of CP (IgG) and history of diabetes    
CP (IgG) neg. and diabetes neg. 1ref 1ref 1ref
CP (IgG) neg. and diabetes pos. 2.21 (1.11–4.40) 2.10 (1.05–4.20) 1.88 (0.93–3.78)
CP (IgG) pos. and diabetes neg. 1.43 (0.81–2.53) 1.41 (0.79–2.50) 1.35 (0.76–2.41)
CP (IgG) pos. and diabetes pos. 3.21 (1.61–6.39) 3.07 (1.53–6.13) 2.77 (1.36–5.64)
Combination of ch-hsp60 and history of diabetes    
Ch-hsp60 neg. and diabetes neg. 1ref 1ref 1ref
Ch-hsp60 neg. and diabetes pos. 2.14 (1.22–3.78) 2.05 (1.15–3.63) 1.78 (1.01–3.18)
Ch-hsp60 pos. and diabetes neg. 1.06 (0.54–2.08) 1.04 (0.53–2.04) 0.93 (0.47–1.84)
Ch-hsp60 pos. and diabetes pos. 2.82 (1.19–6.68) 2.66 (1.12–6.35) 2.55 (1.06–6.17)
  1. a = Adjusted for age and gender
  2. b = Adjusted for age, gender, HDL-cholesterol, smoking, alcohol consumption, school education, marital status, history of myocardial infarction, study centre