Figure 2

SR-BI expression in macrophages from atherosclerotic subjects. Macrophages from 15 atherosclerotic subjects and 15 healthy matched control subjects were treated with mmLDL (50 μg protein/ml) for 24 h. SR-BI expression was analyzed in both groups both before and after mmLDL treatment by real-time RT-PCR. SR-BI expression was normalized to the reference gene RPLP0. The primers for real-time RT-PCR analysis used in this experiment detect SR-BI and the SR-BI isoforms. The results are presented as mean +/- SEM. *, p < 0.05.