Figure 1

Effect of mmLDL on the expression of SR-BI in macrophages. Macrophages from 4 different healthy voluntary donors were exposed to mmLDL (50 μg protein/ml) for 24 h and SR-BI gene expression was analyzed by real-time RT-PCR using RNA from mmLDL treated and untreated control macrophages. The primers for real-time RT-PCR analysis used in this experiment were designed to detect SR-BI and the SR-BI isoforms. SR-BI expression was normalized to the reference gene RPLP0. The results are presented as mean +/- SEM. *, p < 0.005.