From: Predictors and prognosis of paroxysmal atrial fibrillation in general practice in the UK
Paroxysmal AF cases | Controls | |||||
---|---|---|---|---|---|---|
n = 525 | (%) | n = 5000 | (%) | OR* | (95% CI) | |
Age | ||||||
40–49 | 31 | (5.9) | 1565 | (31.3) | 1 | |
50–59 | 62 | (11.8) | 1343 | (26.9) | 2.1 | (1.3–3.2) |
60–69 | 131 | (25.0) | 997 | (19.9) | 5.0 | (3.3–7.5) |
70–79 | 188 | (35.8) | 769 | (15.4) | 8.3 | (5.5–12.5) |
80–89 | 113 | (21.5) | 326 | (6.5) | 10.9 | (7–17.1) |
Sex | ||||||
Female | 268 | (51.0) | 2647 | (52.9) | 1 | |
Male | 257 | (49.0) | 2353 | (47.1) | 1.3 | (1.0–1.6) |
Smoking† | ||||||
Non-smoker | 313 | (59.6) | 2736 | (54.7) | 1 | |
Smoker | 94 | (17.9) | 1226 | (24.5) | 0.8 | (0.6–1.0) |
Ex-smoker | 42 | (8.0) | 280 | (5.6) | 1.0 | (0.7–1.5) |
Body mass index (BMI) † | ||||||
<20 | 25 | (4.8) | 201 | (4.0) | 1.4 | (0.9–2.4) |
20–24 | 135 | (25.7) | 1466 | (29.3) | 1 | |
25–29 | 162 | (30.9) | 1420 | (28.4) | 1.1 | (0.8–1.4) |
30+ | 62 | (11.8) | 601 | (12.0) | 1.1 | (0.8–1.5) |
Alcohol consumption (units per week) †# | ||||||
None | 185 | (35.2) | 1597 | (31.9) | 1 | |
1–7 units | 114 | (21.7) | 1112 | (22.2) | 1.2 | (0.9–1.6) |
8–21 units | 69 | (13.1) | 718 | (14.4) | 1.4 | (1.0–1.9) |
>21 units | 31 | (5.9) | 292 | (5.8) | 1.7 | (1.1–2.6) |
Comorbidity | ||||||
IHD | 156 | (29.7) | 415 | (8.3) | 2.1 | (1.6–2.6) |
Valvular disease | 30 | (5.7) | 41 | (0.8) | 4.2 | (2.4–7.3) |
Heart failure | 81 | (15.4) | 117 | (2.3) | 2.5 | (1.8–3.5) |
Hypertension | 197 | (37.5) | 859 | (17.2) | 1.4 | (1.2–1.8) |
Cerebrovascular disease | 68 | (13.0) | 195 | (3.9) | 1.5 | (1.1–2.1) |
Diabetes | 36 | (6.9) | 194 | (3.9) | 0.9 | (0.6–1.4) |
Hyperthyroidism | 19 | (3.6) | 44 | (0.9) | 3.6 | (2.0–6.5) |