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Table 2 Prevalence of interleukin-1 receptor antagonist gene polymorphisms (IL-1RA) and serostatus of CMV and their combination in patients with and without cardiovascular events during follow-up

From: Prognostic value of interleukin-1 receptor antagonist gene polymorphism and cytomegalovirus seroprevalence in patients with coronary artery disease

 

Patients with Cardiovascular Event (n = 60)

Patients without Cardiovascular Event (n = 240)

p-value

IL-1 RA

   

- othera

55 (91.7%)

215 (89.6%)

 

- Il-1RN*2

5 (8.3%)

25 (10.4%)

0.6

CMV-serostatusb

   

- negative

29 (49.2%)

110 (46.8%)

 

- positive

30 (50.9%)

125 (53.2%)

0.7

IL-1 RA and CMV serostatus

   

- IL-othera and CMV-negative

27 (45.8%)

96 (40.9%)

 

- IL-othera and CMV-positive

27 (45.8%)

114 (48.5%)

 

- Il-1RN*2 and CMV-negative

2 (3.4%)

14 (6.0%)

 

- Il-1RN*2 and CMV-positive

3 (5.1%)

11 (4.7%)

0.8c

  1. a = all other alleles summarized (IL-1RN*4, IL-1RN*5, IL-1RN*3) except IL-RN*2
  2. b = in 6 patients quantitative determination of IgG was not available
  3. c = Fisher exact test