Skip to main content

Table 1 Mean arterial pressure before and after drug administration.

From: Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo

Treatment MAP: pre-drug (mm Hg) MAP: post-drug (mm Hg)
Control   103 ± 5
Ang II   105 ± 7
Ang II + PD 1 mg/kg 122 ± 6 117 ± 10
Ang II + PD 5 mg/kg 119 ± 4 111 ± 5
Ang II + PD 10 mg/kg 115 ± 4 113 ± 2
Irb 2 × 10 mg/kg   75 ± 1
Ang II + Irb 2 × 10 mg/kg   84 ± 2
Control   112 ± 3
R 0.5 mg/kg 98 ± 10 95 ± 10
Ang II   114 ± 7
Ang II + R 0.1 mg/kg 101 ± 9 93 ± 9
Ang II + R 0.5 mg/kg 109 ± 4 109 ± 2
Ang II + R 1.0 mg/kg 111 ± 5 123 ± 1 *
  1. Data are presented as mean ± sem * P < 0.05 vs Pre-drug (paired t-test). † For control and Angiotensin II-treated animals that did not receive further acute treatments, only one pressure is presented. MAP Pre-drug: mean arterial pressure before acute drug administration; MAP post-drug: MAP averaged during the 5 hours following acute drug administration; PD: PD98059; R: Rapamycin; Irb: Irbesartan.