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Table 1 Mean arterial pressure before and after drug administration.

From: Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo

Treatment

MAP: pre-drug (mm Hg)†

MAP: post-drug (mm Hg)

Control

 

103 ± 5

Ang II

 

105 ± 7

Ang II + PD 1 mg/kg

122 ± 6

117 ± 10

Ang II + PD 5 mg/kg

119 ± 4

111 ± 5

Ang II + PD 10 mg/kg

115 ± 4

113 ± 2

Irb 2 × 10 mg/kg

 

75 ± 1

Ang II + Irb 2 × 10 mg/kg

 

84 ± 2

Control

 

112 ± 3

R 0.5 mg/kg

98 ± 10

95 ± 10

Ang II

 

114 ± 7

Ang II + R 0.1 mg/kg

101 ± 9

93 ± 9

Ang II + R 0.5 mg/kg

109 ± 4

109 ± 2

Ang II + R 1.0 mg/kg

111 ± 5

123 ± 1 *

  1. Data are presented as mean ± sem * P < 0.05 vs Pre-drug (paired t-test). † For control and Angiotensin II-treated animals that did not receive further acute treatments, only one pressure is presented. MAP Pre-drug: mean arterial pressure before acute drug administration; MAP post-drug: MAP averaged during the 5 hours following acute drug administration; PD: PD98059; R: Rapamycin; Irb: Irbesartan.