Skip to main content

Table 3 Casewise concordance rates by zygosity and heritability estimates of the four traits

From: A common genetic factor underlies hypertension and other cardiovascular disorders

 

twin type

total pairs

discordant pairs (+/-)

concordant pairs with trait (+/+)

casewise concordance (95% CI)

heritability (95% CI)

HPT

MZ

525

73

29

0.44 (0.34–0.55)

0.64 (0.49–0.79)

 

DZ

577

135

23

0.25 (0.17–0.34)

 

RP

MZ

525

75

18

0.32 (0.21–0.44)

0.46 (0.30–0.63)

 

DZ

577

111

10

0.15 (0.07–0.24)

 

MIG

MZ

525

144

60

0.46 (0.38–0.53)

0.43 (0.30–0.55)

 

DZ

577

186

40

0.30 (0.23–0.37)

 

CAD

MZ

525

55

8

0.23 (0.10–0.35)

0.34 (0.13–0.55)

 

DZ

577

72

2

0.05 (0.00–0.12)

 
  1. Casewise concordance rates (95% confidence intervals, CI) are shown for each trait by zygosity. An estimate of trait heritability (95% CI) is also given.
  2. HPT represents hypertension, RP Raynaud's phenomenon, MIG migraine, CAD coronary artery disease.