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Table 2 Subject characteristics in relation to the TNF-α G-308 polymorphism

From: Effect of the G-308A polymorphism of the tumor necrosis factor (TNF)-α gene promoter site on plasma levels of TNF-α and C-reactive protein in smokers: a cross-sectional study

 

GG n = 203

GA/AA n = 73

P-value

Gender [% male]

87

86

0.73

Age [years]

41.0 ± 9.1

42.9 ± 9.4

0.37

Regular smokers [%]

28.3

21.8

0.26

Low-density lipoprotein cholesterol [mg/dl]

119.5 ± 32.6

124.8 ± 29.1

0.22

High-density lipoprotein cholesterol [mg/dl]

44.1 ± 11.9

44.62 ± 10.9

0.76

Systolic blood pressure [mmHg]

131.7 ± 11.7

134.6 ± 17.4

0.18

Diastolic blood pressure [mmHg]

82.5 ± 11.1

82.7 ± 8.1

0.87

Glycosylated hemoglobin A1c [%]

5.1 ± 0.5

5.2 ± 0.6

0.18

Tumor necrosis factor-α [ng/l]

1.7 (1.3–2.2)

1.9 (1.4–2.2)

0.39

C-reactive protein [mg/l]

1.04 (0.53–2.36)

1.05 (0.49–3.14)

0.35

  1. Tumor necrosis factor (TNF)-α and C-reactive protein (CRP) levels were compared by the Wilcoxon test; for all other continuous variables the Student t-test was employed. Values are means ± SD except for TNF-α and CRP where the median and interquartile range is provided.