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Table 1 Demographics, stroke risk factors and clinical characteristics of the study population.

From: Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690]

Demographics    
  Acetaminophen (n = 26) Ibuprofen (n = 24) Placebo (n = 25)
Age in years (m, SD) 69 (16) 67 (15) 65 (10)
Male sex 17 (65%) 16 (67%) 16 (64%)
Risk factors for stroke    
Hypertension 12 (46%) 7 (29%) 8 (32%)
Atrial fibrillation 6 (24%) 7 (29%) 1 (4%)
Peripheral vascular disease 4 (15%) 1 (4%) 1 (4%)
Diabetes mellitus 1 (4%) 4 (17%) 3 (12%)
Previous TIA 5 (19%) 3 (13%) 3 (12%)
Previous stroke 3 (12%) 8 (33%) 2 (8%)
Cigarette smoking 14 (54%) 13 (54%) 16 (64%)
Stroke characteristics    
Lowered consciousness level 5 (19%) 2 (8%) 2 (8%)
Aphasia 7 (27%) 9 (37%) 6 (24%)
NIHSS (m, SD) 18 (14) 12 (10) 14 (11)
Lacunar stroke 8 (31%) 6 (25%) 11 (44%)
Other clinical characteristics    
Treatment within 0–12 hours 14 (54%) 14 (58%) 12 (48%)
Temp. at admission (°C) (m, SD) 37.2 (0.6) 37.0 (0.6) 37.0 (0.5)
Temp. at start of treatment (°C) (m, SD) 37.3 (0.5) 37.1 (0.7) 37.0 (0.5)
  1. Acetaminophen is given in a dose of 1000 mgs, 6 times daily, and ibuprofen in a dose of 400 mg 6 times daily. Values are absolute numbers with percentages of totals in the treatment arms, unless stated otherwise. 'm' indicates mean, 'SD' standard deviation.