Skip to main content

Table 1 Demographics, stroke risk factors and clinical characteristics of the study population.

From: Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690]

Demographics

   
 

Acetaminophen (n = 26)

Ibuprofen (n = 24)

Placebo (n = 25)

Age in years (m, SD)

69 (16)

67 (15)

65 (10)

Male sex

17 (65%)

16 (67%)

16 (64%)

Risk factors for stroke

   

Hypertension

12 (46%)

7 (29%)

8 (32%)

Atrial fibrillation

6 (24%)

7 (29%)

1 (4%)

Peripheral vascular disease

4 (15%)

1 (4%)

1 (4%)

Diabetes mellitus

1 (4%)

4 (17%)

3 (12%)

Previous TIA

5 (19%)

3 (13%)

3 (12%)

Previous stroke

3 (12%)

8 (33%)

2 (8%)

Cigarette smoking

14 (54%)

13 (54%)

16 (64%)

Stroke characteristics

   

Lowered consciousness level

5 (19%)

2 (8%)

2 (8%)

Aphasia

7 (27%)

9 (37%)

6 (24%)

NIHSS (m, SD)

18 (14)

12 (10)

14 (11)

Lacunar stroke

8 (31%)

6 (25%)

11 (44%)

Other clinical characteristics

   

Treatment within 0–12 hours

14 (54%)

14 (58%)

12 (48%)

Temp. at admission (°C) (m, SD)

37.2 (0.6)

37.0 (0.6)

37.0 (0.5)

Temp. at start of treatment (°C) (m, SD)

37.3 (0.5)

37.1 (0.7)

37.0 (0.5)

  1. Acetaminophen is given in a dose of 1000 mgs, 6 times daily, and ibuprofen in a dose of 400 mg 6 times daily. Values are absolute numbers with percentages of totals in the treatment arms, unless stated otherwise. 'm' indicates mean, 'SD' standard deviation.